Balance Sheet Items - Summary of Accrued expenses and other current liabilities (Detail) - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Payables and Accruals [Abstract]
Accrued research and development expenses	$ 6,810	$ 3,308
Accrued payroll related expenses	5,046	2,565
Accrued professional service expenses	1,527	732
Other	453	104
Total accrued expenses and other current liabilities	$ 13,836	$ 6,709