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Condensed Consolidated Statements of Cash Flows (unaudited) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Cash flows from operating activities    
Net loss $ (64,277) $ (31,575)
Adjustments to reconcile net loss to net cash used in operating activities:    
Acquired in-process research and development assets 0 8,000
Share-based compensation expense 11,833 3,075
Depreciation expense 12 10
Amortization of operating right-of-use assets 174 88
Non-cash interest expense 0 14
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (2,580) (4,722)
Deposits and other long-term assets (315) (19)
Accounts payable (1,305) 145
Accrued expenses and other current liabilities 5,224 1,937
Operating lease liabilities (116) (102)
Net cash used in operating activities (51,350) (23,149)
Cash flows from investing activities    
Cash paid for acquired in-process research and development assets 0 (8,000)
Cash paid for purchase of short-term investments (5,990) 0
Cash paid for property and equipment (22) 0
Cash used in investing activities (6,012) (8,000)
Cash flows from financing activities    
Proceeds from issuance of Series B redeemable convertible preferred shares, net of issuance costs 0 129,757
Proceeds from issuance of common stock, net 161,610 167,660
Proceeds from issuance of common stock upon ESPP purchase 320 0
Net cash provided by financing activities 161,930 297,417
Net increase in cash and cash equivalents 104,568 266,268
Cash and cash equivalents, beginning of period 284,309 43,728
Cash and cash equivalents, end of period 388,877 309,996
Supplemental disclosures of noncash activities    
Lease liability obtained in exchange for right-of-use asset 940 0
Deferred offering costs not yet paid 519 615
Exchange of 45,331,483 preferred, common, and incentive shares in connection with the Conversion (Note 1) 0 224,892
Exchange of redeemable convertible noncontrolling interest to 6,470,382 shares of common stock (Note 11) $ 0 $ 3,592