Commitment and Contingencies - Additional Information (Detail) $ in Thousands	1 Months Ended	3 Months Ended		6 Months Ended
	Apr. 30, 2022 USD ($) ft²	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Dec. 31, 2021 USD ($)
Lessee, Lease, Description [Line Items]
Amortization of operating right-of-use assets				$ 174	$ 88
Weighted Average Remaining Lease Term		2 years 2 months 12 days		2 years 2 months 12 days
Weighted Average Discount Rate Percent		8.90%		8.90%
Research And Development Agreements
Lessee, Lease, Description [Line Items]
Termination and cancellation charges payable		$ 0		$ 0		$ 0
Viracta License Agreement
Lessee, Lease, Description [Line Items]
Royalty fee payable		0		0		0
Indemnification Agreement
Lessee, Lease, Description [Line Items]
Termination and cancellation charges payable		0		0		$ 0
Central America
Lessee, Lease, Description [Line Items]
Operating lease term	31 months
Sublease agreement area | ft²	12,000
Operating lease payments	$ 1,100
Security Deposit	$ 40,000
Lease For Corporate Office Facility | Central America
Lessee, Lease, Description [Line Items]
Tenant improvement allowances receivable		$ 10,000		$ 10,000
Lessee operating lease renewal lease term		3 years		3 years
Amortization of operating right-of-use assets		$ 148,000	$ 44,000	$ 195,000	88,000
Operating lease payments				$ 143,000	$ 102,000