Balance Sheet Items - Summary of Accrued expenses and other current liabilities (Detail) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Payables and Accruals [Abstract]
Accrued payroll related expenses	$ 1,648	$ 3,308
Accrued research and development expenses	4,171	2,565
Accrued professional service expenses	1,098	732
Other	387	104
Total accrued expenses and other current liabilities	$ 7,304	$ 6,709