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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Cash flows from operating activities      
Net loss $ (72,754) $ (43,843) $ (16,984)
Adjustments to reconcile net loss to net cash used in operating activities:      
Acquired in-process research and development assets 8,000 0  
Share-based compensation expense 13,321 526 111
Depreciation and amortization expense 20 16 0
Amortization of operating right-of-use assets 179 139
Non-cash interest expense 0 30 2,077
Issuance of shares for research and development 0 9,837
Changes in derivative tranche liabilities 0 30,000 0
Changes in operating assets and liabilities:      
Prepaid expenses and other current assets (3,717) (1,336) (4)
Deposits and other long-term assets (62) (107) 0
Accounts payable 1,542 132 14
Accrued expenses and other current liabilities 5,114 1,127 434
Operating lease liabilities (182) (173)
Net cash used in operating activities (48,539) (13,489) (4,515)
Cash flows from investing activities      
Purchases of property and equipment 0 (92) 0
Cash paid for acquired in-process research and development assets (8,000) 0 0
Cash used in investing activities (8,000) (92) 0
Cash flows from financing activities      
Proceeds from issuance of convertible notes 0 0 1,000
Proceeds from issuance of common stock, net 167,045 0
Proceeds from issuance of common stock upon ESPP purchase 318   0
Net cash provided by financing activities 297,120 29,977 30,905
Cash and Cash Equivalents, Period Increase (Decrease), Total 240,581 16,396 26,390
Cash and cash equivalents, beginning of period 43,728 27,332 942
Cash and cash equivalents, end of period 284,309 43,728 27,332
Supplemental disclosures of noncash activities      
Recognition of contingent beneficial conversion feature upon notes conversion 0 0 2,000
Issuance of Series A redeemable convertible shares for research and development 0 0 9,857
Conversion of convertible notes and accrued interest into Series A redeemable convertible preferred shares 0 0 2,082
Issuance of derivative tranches liability 0 0 1,483
Transfers to redeemable convertible noncontrolling interest 0 3,551 0
Right of use asset capitalization 0 545 0
Exchange of 45,331,483 preferred, common, and incentive shares in connection with the Conversion (Note 1) 224,892 0 0
Exchange of redeemable convertible noncontrolling interest to 6,470,382 shares of common stock (Note 13) 3,592 0 0
Series A Preferred Stock [Member]      
Cash flows from financing activities      
Proceeds from issuance of redeemable convertible preferred shares, net of issuance costs 0 29,977 29,905
Series B Preferred Stock [Member]      
Cash flows from financing activities      
Proceeds from issuance of redeemable convertible preferred shares, net of issuance costs $ 129,757 $ 0 $ 0