Skadden, Arps, Slate, Meagher & Flom llp

One manhattan west

New York, New York 10001

       DIRECT DIAL
(212) 735-3574
       DIRECT FAX
(917) 777-3574
       EMAIL ADDRESS
David.Goldschmidt@SKADDEN.COM


TEL: (212) 735-3000
FAX: (212) 735-2000
www.skadden.com FIRM/AFFILIATE
OFFICES
_____
BOSTON
CHICAGO
HOUSTON
LOS ANGELES
NEW YORK
WASHINGTON, D.C.
WILMINGTON
_____
BEIJING
BRUSSELS
FRANKFURT
HONG KONG
LONDON
MOSCOW
MUNICH
PARIS
SÃO PAULO
SEOUL
SHANGHAI
SINGAPORE
TOKYO
TORONTO

March 11, 2021

VIA EDGAR

Maryse Mills-Apenteng

Division of Corporation Finance

Office of Real Estate & Construction

U.S. Securities and Exchange Commission

100 F Street, NE

Washington, D.C. 20549

RE: NextGen Acquisition Corp. II

Draft Registration Statement Submitted February 10, 2021

CIK No. 0001843388

Form S-1 Filed March 4, 2021

File No. 333-253848

Dear Mrs. Mills-Apenteng:

On behalf of NextGen Acquisition Corp. II (the “Company” or “we”), in connection with the proposed initial public offering of the Company’s securities, we submit the below in response to the comment of the staff (“Staff”) of the Division of Corporation Finance of the U.S. Securities and Exchange Commission received by letter dated March 9, 2021, concerning the Company’s Registration Statement on Form S-1 filed on March 4, 2021.

1. Draft Registration Statement on Form S-1

a. General

i. Please include a bullet point summary of your principal risks in the forepart of the prospectus as required by Item 105(b) of Regulation S-K.

The Company will revise the prospectus to include the bullet point summary as required by Item 105(b) in the next amended S-1 filing.

*   *   *

U.S. Securities and Exchange Commission

March 11, 2021

Page 2

Please contact me at (212) 735-3574 should you require further information.

Very truly yours,

/s/ David J. Goldschmidt

David J. Goldschmidt

cc: NextGen Acquisition Corp. II

Patrick T. Ford

cc: Ropes & Gray LLP

Paul Tropp, Esq. and Emily Oldshue, Esq.