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Share-Based Compensation (Tables)
 9 Months Ended
Sep. 30, 2025
Share-Based Payment Arrangement [Abstract]  
Share-Based Payment Arrangement, Expensed and Capitalized, Amount
Share-based compensation expense related to the issuance of stock options was as follows for the three and nine months ended September 30, 2025 and 2024:
Three Months Ended September 30,Nine Months Ended September 30,
2025202420252024
Research and development$29,271 $25,811 $204,940 $21,765 
General and administrative293,810 187,191 800,972 588,281 
$323,081 $213,002 $1,005,912 $610,046 
Schedule of Assumptions Used to Determine Fair Value of Share-Based Awards
The weighted average assumptions used in the Black-Scholes option pricing model to determine the fair value of share-based awards granted during the nine months ended September 30, 2025 and 2024 were as follows:
 
 20252024
Expected stock price volatility111.99%95.52%
Risk-free interest rate4.30%4.13%
Expected term (in years)5.946.00
Expected dividend yield——
Schedule of Share-Based Award Activity
The following table summarizes the share-based award activity for the periods presented:
 
 
Number of Shares
Weighted Average
Exercise Price Per
Share 		Weighted Average
Remaining
Contractual Term
(years)
Aggregate Intrinsic Value
Outstanding at January 1, 20253,273,615$1.97 8.2$176,045 
Granted3,254,660$0.77  
     Forfeited
(689,775)$1.73 
Outstanding at September 30, 2025
5,838,500$1.33 8.4$712,194 
Vested and exercisable at September 30, 2025
2,009,009$2.26 7.0$68,103 
Vested and expected to vest at September 30, 2025
5,838,500$1.33 8.4$712,194