ALKERMES PLC SHS G01767105 8439477 238673 SH SOLE 238673 0 0 ARGENX SE SPONSORED ADR 04016X101 55744364 76336 SH SOLE 76336 0 0 ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 19819455 86650 SH SOLE 86650 0 0 ATAIBECKLEY INC COM SHS 04650F101 6051131 1709359 SH SOLE 1709359 0 0 BIOMARIN PHARMACEUTICAL INC COM 09061G101 28573150 505809 SH SOLE 505809 0 0 BOSTON SCIENTIFIC CORP COM 101137107 18395288 293152 SH SOLE 293152 0 0 BRIDGEBIO PHARMA INC COM 10806X102 19829722 267031 SH SOLE 267031 0 0 CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100 8511639 214291 SH SOLE 214291 0 0 COMPASS PATHWAYS PLC SPONSORED ADS 20451W101 11394161 2060427 SH SOLE 2060427 0 0 FORTREA HLDGS INC COMMON STOCK 34965K107 12317215 1307560 SH SOLE 1307560 0 0 GUARDANT HEALTH INC COM 40131M109 28660656 310281 SH SOLE 310281 0 0 ICON PLC SHS G4705A100 39671610 358500 SH SOLE 358500 0 0 ILLUMINA INC COM 452327109 23100526 187413 SH SOLE 187413 0 0 IMMUNOCORE HLDGS PLC ADS 45258D105 1395945 46300 SH SOLE 46300 0 0 INSMED INC COM PAR $.01 457669307 36672794 224271 SH SOLE 224271 0 0 INTUITIVE SURGICAL INC COM NEW 46120E602 2023746 4390 SH SOLE 4390 0 0 KYMERA THERAPEUTICS INC COM 501575104 12145015 145816 SH SOLE 145816 0 0 NATERA INC COM 632307104 24374181 121877 SH SOLE 121877 0 0 PERCEPTIVE CAP SOLUTIONS COR CL A ORD SHS G70077105 413415 37686 SH SOLE 37686 0 0 PROCEPT BIOROBOTICS CORP COM 74276L105 12100213 483815 SH SOLE 483815 0 0 PROCEPT BIOROBOTICS CORP COM 74276L105 2250900 90000 SH Call SOLE 90000 0 0 PROTAGONIST THERAPEUTICS INC COM 74366E102 18900539 179322 SH SOLE 179322 0 0 REVOLUTION MEDICINES INC COM 76155X100 11617874 119464 SH SOLE 119464 0 0 SCHOLAR ROCK HLDG CORP COM 80706P103 24285974 494019 SH SOLE 494019 0 0 SPDR SERIES TRUST STATE STREET SPD 78464A870 93242900 730000 SH Put SOLE 730000 0 0 TEMPUS AI INC CL A 88023B103 11588484 256269 SH SOLE 256269 0 0 TERNS PHARMACEUTICALS INC COM 880881107 21746842 412497 SH SOLE 412497 0 0 ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 18522335 884121 SH SOLE 884121 0 0