The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
PDD Holdings Inc ADR 722304102   315,775 4,567,173 SH   DFND   4,567,173 0 0
KE Holdings Inc ADR 482497104   76,015 5,118,823 SH   DFND   5,118,823 0 0
Taiwan Semiconductor Manufactu ADR 874039100   66,850 662,408 SH   DFND   662,408 0 0
Microsoft Corp Common Stock 594918104   63,566 186,660 SH   DFND   186,660 0 0
STAAR Surgical Co Common Stock 852312305   47,434 902,296 SH   SOLE   902,296 0 0
Sea Ltd ADR 81141R100   42,775 737,000 SH   SOLE   737,000 0 0
Apple Inc Common Stock 037833100   42,249 217,810 SH   SOLE   217,810 0 0
Grab Holdings Ltd Common Stock G4124C109   40,920 11,930,000 SH   SOLE   11,930,000 0 0
Vipshop Holdings Ltd ADR 92763W103   38,452 2,330,385 SH   DFND   2,330,385 0 0
Advanced Micro Devices Inc Common Stock 007903107   36,415 319,678 SH   SOLE   319,678 0 0
Kanzhun Ltd ADR 48553T106   35,170 2,336,870 SH   DFND   2,336,870 0 0
Full Truck Alliance Co Ltd ADR 35969L108   33,977 5,462,564 SH   SOLE   5,462,564 0 0
Tencent Music Entertainment Gr ADR 88034P109   30,563 4,141,328 SH   DFND   4,141,328 0 0
ASML Holding NV NY Reg Shrs N07059210   30,535 42,131 SH   DFND   42,131 0 0
NVIDIA Corp Common Stock 67066G104   23,001 54,373 SH   DFND   54,373 0 0
Yum China Holdings Inc Common Stock 98850P109   21,246 376,043 SH   DFND   376,043 0 0
TAL Education Group ADR 874080104   18,191 3,052,228 SH   DFND   3,052,228 0 0
iQIYI Inc ADR 46267X108   17,295 3,238,840 SH   DFND   3,238,840 0 0
Qifu Technology Inc ADR 88557W101   15,639 905,032 SH   DFND   905,032 0 0
Autohome Inc ADR 05278C107   12,967 444,677 SH   DFND   444,677 0 0
NIO Inc ADR 62914V106   11,905 1,228,592 SH   DFND   1,228,592 0 0
Tesla Inc Common Stock 88160R101   10,235 39,102 SH   DFND   39,102 0 0
Amazon.com Inc Common Stock 023135106   9,795 75,140 SH   DFND   75,140 0 0
ZTO Express Cayman Inc ADR 98980A105   9,505 378,976 SH   DFND   378,976 0 0
KLA Corp Common Stock 482480100   7,938 16,366 SH   SOLE   16,366 0 0
Lufax Holding Ltd ADR 54975P102   7,571 5,294,177 SH   DFND   5,294,177 0 0
H World Group Ltd ADR 44332N106   6,716 173,182 SH   DFND   173,182 0 0
Broadcom Inc Common Stock 11135F101   6,169 7,112 SH   SOLE   7,112 0 0
Meta Platforms Inc Common Stock 30303M102   5,801 20,214 SH   SOLE   20,214 0 0
Alphabet Inc Common Stock 02079K305   5,742 47,972 SH   SOLE   47,972 0 0
Alphabet Inc Common Stock 02079K107   5,123 42,346 SH   SOLE   42,346 0 0
QUALCOMM Inc Common Stock 747525103   4,054 34,056 SH   SOLE   34,056 0 0
Adobe Inc Common Stock 00724F101   3,826 7,825 SH   SOLE   7,825 0 0
Cisco Systems Inc Common Stock 17275R102   3,606 69,696 SH   SOLE   69,696 0 0
Legend Biotech Corp ADR 52490G102   3,567 51,679 SH   DFND   51,679 0 0
ServiceNow Inc Common Stock 81762P102   2,795 4,972 SH   DFND   4,972 0 0
Texas Instruments Inc Common Stock 882508104   2,787 15,480 SH   SOLE   15,480 0 0
Intel Corp Common Stock 458140100   2,379 71,133 SH   SOLE   71,133 0 0
PepsiCo Inc Common Stock 713448108   2,332 12,589 SH   SOLE   12,589 0 0
Marriott International Inc/MD Common Stock 571903202   2,192 11,933 SH   SOLE   11,933 0 0
Intuit Inc Common Stock 461202103   2,191 4,782 SH   SOLE   4,782 0 0
Costco Wholesale Corp Common Stock 22160K105   2,182 4,053 SH   SOLE   4,053 0 0
Daqo New Energy Corp ADR 23703Q203   2,130 53,656 SH   DFND   53,656 0 0
Micron Technology Inc Common Stock 595112103   2,110 33,431 SH   DFND   33,431 0 0
Applied Materials Inc Common Stock 038222105   2,086 14,434 SH   SOLE   14,434 0 0
iShares Core S&P 500 ETF ETP 464287200   2,048 4,596 SH   DFND   4,596 0 0
Salesforce Inc Common Stock 79466L302   1,983 9,386 SH   SOLE   9,386 0 0
Accenture PLC Common Stock G1151C101   1,868 6,055 SH   SOLE   6,055 0 0
Netflix Inc Common Stock 64110L106   1,790 4,063 SH   SOLE   4,063 0 0
Oracle Corp Common Stock 68389X105   1,757 14,753 SH   SOLE   14,753 0 0
Lululemon Athletica Inc Common Stock 550021109   1,716 4,533 SH   SOLE   4,533 0 0
Analog Devices Inc Common Stock 032654105   1,699 8,721 SH   SOLE   8,721 0 0
Amgen Inc Common Stock 031162100   1,641 7,392 SH   SOLE   7,392 0 0
Comcast Corp Common Stock 20030N101   1,579 38,007 SH   SOLE   38,007 0 0
Lam Research Corp Common Stock 512807108   1,495 2,326 SH   SOLE   2,326 0 0
Estee Lauder Cos Inc/The Common Stock 518439104   1,449 7,379 SH   SOLE   7,379 0 0
MINISO Group Holding Ltd ADR 66981J102   1,440 84,778 SH   DFND   84,778 0 0
SPDR S&P 500 ETF Trust ETP 78462F103   1,434 3,236 SH   DFND   3,236 0 0
Gilead Sciences Inc Common Stock 375558103   1,418 18,404 SH   SOLE   18,404 0 0
Vertex Pharmaceuticals Inc Common Stock 92532F100   1,404 3,991 SH   SOLE   3,991 0 0
T-Mobile US Inc Common Stock 872590104   1,378 9,922 SH   SOLE   9,922 0 0
Marvell Technology Inc Common Stock 573874104   1,360 22,757 SH   SOLE   22,757 0 0
Palo Alto Networks Inc Common Stock 697435105   1,345 5,263 SH   SOLE   5,263 0 0
Carnival Corp Common Stock 143658300   1,343 71,320 SH   SOLE   71,320 0 0
NIKE Inc Common Stock 654106103   1,292 11,702 SH   SOLE   11,702 0 0
Honeywell International Inc Common Stock 438516106   1,262 6,083 SH   SOLE   6,083 0 0
JOYY Inc ADR 46591M109   1,245 40,532 SH   DFND   40,532 0 0
Regeneron Pharmaceuticals Inc Common Stock 75886F107   1,236 1,720 SH   SOLE   1,720 0 0
Intuitive Surgical Inc Common Stock 46120E602   1,206 3,528 SH   SOLE   3,528 0 0
International Business Machine Common Stock 459200101   1,165 8,706 SH   SOLE   8,706 0 0
Synopsys Inc Common Stock 871607107   1,143 2,626 SH   SOLE   2,626 0 0
Cadence Design Systems Inc Common Stock 127387108   1,102 4,701 SH   SOLE   4,701 0 0
Starbucks Corp Common Stock 855244109   1,046 10,557 SH   SOLE   10,557 0 0
Berkshire Hathaway Inc Common Stock 084670702   1,016 2,979 SH   SOLE   2,979 0 0
Rambus Inc Common Stock 750917106   951 14,822 SH   SOLE   14,822 0 0
Moderna Inc Common Stock 60770K107   945 7,781 SH   SOLE   7,781 0 0
MongoDB Inc Common Stock 60937P106   928 2,258 SH   SOLE   2,258 0 0
AbbVie Inc Common Stock 00287Y109   924 6,860 SH   SOLE   6,860 0 0
Fortinet Inc Common Stock 34959E109   924 12,230 SH   SOLE   12,230 0 0
Booking Holdings Inc Common Stock 09857L108   921 341 SH   SOLE   341 0 0
NXP Semiconductors NV Common Stock N6596X109   916 4,477 SH   SOLE   4,477 0 0
Mondelez International Inc Common Stock 609207105   915 12,542 SH   SOLE   12,542 0 0
Datadog Inc Common Stock 23804L103   881 8,960 SH   SOLE   8,960 0 0
Biogen Inc Common Stock 09062X103   875 3,072 SH   SOLE   3,072 0 0
iShares iBoxx $ Investment Gra ETP 464287242   854 7,900 SH   DFND   7,900 0 0
Microchip Technology Inc Common Stock 595017104   844 9,424 SH   SOLE   9,424 0 0
UnitedHealth Group Inc Common Stock 91324P102   839 1,745 SH   SOLE   1,745 0 0
Automatic Data Processing Inc Common Stock 053015103   836 3,805 SH   SOLE   3,805 0 0
Weibo Corp ADR 948596101   831 63,392 SH   DFND   63,392 0 0
Johnson & Johnson Common Stock 478160104   815 4,925 SH   SOLE   4,925 0 0
Autodesk Inc Common Stock 052769106   755 3,692 SH   SOLE   3,692 0 0
ON Semiconductor Corp Common Stock 682189105   741 7,834 SH   SOLE   7,834 0 0
Exxon Mobil Corp Common Stock 30231G102   724 6,752 SH   SOLE   6,752 0 0
Eli Lilly & Co Common Stock 532457108   716 1,526 SH   SOLE   1,526 0 0
Seagen Inc Common Stock 81181C104   715 3,713 SH   SOLE   3,713 0 0
JPMorgan Chase & Co Common Stock 46625H100   710 4,881 SH   SOLE   4,881 0 0
PayPal Holdings Inc Common Stock 70450Y103   686 10,275 SH   SOLE   10,275 0 0
Royal Caribbean Cruises Ltd Common Stock V7780T103   679 6,541 SH   SOLE   6,541 0 0
Visa Inc Common Stock 92826C839   642 2,703 SH   SOLE   2,703 0 0
CSX Corp Common Stock 126408103   634 18,578 SH   SOLE   18,578 0 0
Activision Blizzard Inc Common Stock 00507V109   612 7,256 SH   SOLE   7,256 0 0
Procter & Gamble Co/The Common Stock 742718109   597 3,937 SH   SOLE   3,937 0 0
Merck & Co Inc Common Stock 58933Y105   587 5,084 SH   SOLE   5,084 0 0
Cognizant Technology Solutions Common Stock 192446102   579 8,873 SH   SOLE   8,873 0 0
Incyte Corp Common Stock 45337C102   571 9,167 SH   SOLE   9,167 0 0
Dexcom Inc Common Stock 252131107   552 4,296 SH   SOLE   4,296 0 0
Mastercard Inc Common Stock 57636Q104   550 1,398 SH   SOLE   1,398 0 0
O'Reilly Automotive Inc Common Stock 67103H107   532 557 SH   SOLE   557 0 0
Home Depot Inc/The Common Stock 437076102   526 1,692 SH   SOLE   1,692 0 0
Monster Beverage Corp Common Stock 61174X109   522 9,094 SH   SOLE   9,094 0 0
Catalyst Pharmaceuticals Inc Common Stock 14888U101   517 38,438 SH   SOLE   38,438 0 0
Roper Technologies Inc Common Stock 776696106   503 1,046 SH   SOLE   1,046 0 0
ANSYS Inc Common Stock 03662Q105   501 1,516 SH   SOLE   1,516 0 0
IDEXX Laboratories Inc Common Stock 45168D104   495 985 SH   SOLE   985 0 0
Amphenol Corp Common Stock 032095101   494 5,815 SH   SOLE   5,815 0 0
Blueprint Medicines Corp Common Stock 09627Y109   483 7,639 SH   SOLE   7,639 0 0
Motorola Solutions Inc Common Stock 620076307   481 1,639 SH   SOLE   1,639 0 0
Bridgebio Pharma Inc Common Stock 10806X102   480 27,916 SH   SOLE   27,916 0 0
Charter Communications Inc Common Stock 16119P108   478 1,302 SH   SOLE   1,302 0 0
Exact Sciences Corp Common Stock 30063P105   478 5,087 SH   SOLE   5,087 0 0
Halozyme Therapeutics Inc Common Stock 40637H109   474 13,152 SH   SOLE   13,152 0 0
REVOLUTION Medicines Inc Common Stock 76155X100   467 17,469 SH   SOLE   17,469 0 0
Horizon Therapeutics Plc Common Stock G46188101   463 4,501 SH   SOLE   4,501 0 0
IVERIC bio Inc Common Stock 46583P102   461 11,717 SH   SOLE   11,717 0 0
Chevron Corp Common Stock 166764100   458 2,911 SH   SOLE   2,911 0 0
Twist Bioscience Corp Common Stock 90184D100   455 22,246 SH   SOLE   22,246 0 0
Apellis Pharmaceuticals Inc Common Stock 03753U106   452 4,963 SH   SOLE   4,963 0 0
Arrowhead Pharmaceuticals Inc Common Stock 04280A100   451 12,646 SH   SOLE   12,646 0 0
Ionis Pharmaceuticals Inc Common Stock 462222100   451 10,988 SH   SOLE   10,988 0 0
Neurocrine Biosciences Inc Common Stock 64125C109   451 4,783 SH   SOLE   4,783 0 0
Cintas Corp Common Stock 172908105   450 905 SH   SOLE   905 0 0
Alkermes PLC Common Stock G01767105   449 14,348 SH   SOLE   14,348 0 0
Natera Inc Common Stock 632307104   449 9,232 SH   SOLE   9,232 0 0
Alnylam Pharmaceuticals Inc Common Stock 02043Q107   445 2,341 SH   SOLE   2,341 0 0
Exelixis Inc Common Stock 30161Q104   445 23,263 SH   SOLE   23,263 0 0
MercadoLibre Inc Common Stock 58733R102   444 375 SH   SOLE   375 0 0
Novavax Inc Common Stock 670002401   444 59,792 SH   SOLE   59,792 0 0
Beam Therapeutics Inc Common Stock 07373V105   443 13,867 SH   SOLE   13,867 0 0
Vaxcyte Inc Common Stock 92243G108   441 8,834 SH   SOLE   8,834 0 0
Prothena Corp PLC Common Stock G72800108   439 6,427 SH   SOLE   6,427 0 0
Amicus Therapeutics Inc Common Stock 03152W109   438 34,867 SH   SOLE   34,867 0 0
GE HealthCare Technologies Inc Common Stock 36266G107   436 5,361 SH   SOLE   5,361 0 0
Pfizer Inc Common Stock 717081103   434 11,829 SH   SOLE   11,829 0 0
ACADIA Pharmaceuticals Inc Common Stock 004225108   433 18,068 SH   SOLE   18,068 0 0
TE Connectivity Ltd Common Stock H84989104   432 3,079 SH   SOLE   3,079 0 0
United Therapeutics Corp Common Stock 91307C102   432 1,955 SH   SOLE   1,955 0 0
Thermo Fisher Scientific Inc Common Stock 883556102   431 826 SH   SOLE   826 0 0
Chinook Therapeutics Inc Common Stock 16961L106   430 11,196 SH   SOLE   11,196 0 0
Las Vegas Sands Corp Common Stock 517834107   430 7,406 SH   SOLE   7,406 0 0
Karuna Therapeutics Inc Common Stock 48576A100   426 1,963 SH   SOLE   1,963 0 0
Mirati Therapeutics Inc Common Stock 60468T105   425 11,760 SH   SOLE   11,760 0 0
BioMarin Pharmaceutical Inc Common Stock 09061G101   424 4,889 SH   SOLE   4,889 0 0
Protagonist Therapeutics Inc Common Stock 74366E102   424 15,354 SH   SOLE   15,354 0 0
Relay Therapeutics Inc Common Stock 75943R102   423 33,708 SH   SOLE   33,708 0 0
PTC Therapeutics Inc Common Stock 69366J200   422 10,387 SH   SOLE   10,387 0 0
Insmed Inc Common Stock 457669307   421 19,953 SH   SOLE   19,953 0 0
Intellia Therapeutics Inc Common Stock 45826J105   421 10,330 SH   SOLE   10,330 0 0
Abbott Laboratories Common Stock 002824100   417 3,826 SH   SOLE   3,826 0 0
Ironwood Pharmaceuticals Inc Common Stock 46333X108   415 38,989 SH   SOLE   38,989 0 0
Travere Therapeutics Inc Common Stock 89422G107   412 26,794 SH   SOLE   26,794 0 0
Vir Biotechnology Inc Common Stock 92764N102   411 16,762 SH   SOLE   16,762 0 0
CRISPR Therapeutics AG Common Stock H17182108   409 7,294 SH   SOLE   7,294 0 0
89bio Inc Common Stock 282559103   409 21,604 SH   SOLE   21,604 0 0
TG Therapeutics Inc Common Stock 88322Q108   404 16,266 SH   SOLE   16,266 0 0
Enphase Energy Inc Common Stock 29355A107   401 2,395 SH   SOLE   2,395 0 0
Morphic Holding Inc Common Stock 61775R105   401 6,991 SH   SOLE   6,991 0 0
Ultragenyx Pharmaceutical Inc Common Stock 90400D108   401 8,693 SH   SOLE   8,693 0 0
Sarepta Therapeutics Inc Common Stock 803607100   401 3,499 SH   SOLE   3,499 0 0
PACCAR Inc Common Stock 693718108   400 4,776 SH   SOLE   4,776 0 0
Iovance Biotherapeutics Inc Common Stock 462260100   399 56,609 SH   SOLE   56,609 0 0
Akero Therapeutics Inc Common Stock 00973Y108   397 8,510 SH   SOLE   8,510 0 0
American Electric Power Co Inc Common Stock 025537101   396 4,705 SH   SOLE   4,705 0 0
Arista Networks Inc Common Stock 040413106   396 2,441 SH   SOLE   2,441 0 0
Airbnb Inc Common Stock 009066101   395 3,080 SH   SOLE   3,080 0 0
Denali Therapeutics Inc Common Stock 24823R105   394 13,361 SH   SOLE   13,361 0 0
Cytokinetics Inc Common Stock 23282W605   393 12,062 SH   SOLE   12,062 0 0
Copart Inc Common Stock 217204106   391 4,283 SH   SOLE   4,283 0 0
Coca-Cola Co/The Common Stock 191216100   391 6,500 SH   SOLE   6,500 0 0
Roivant Sciences Ltd Common Stock G76279101   390 38,725 SH   SOLE   38,725 0 0
Madrigal Pharmaceuticals Inc Common Stock 558868105   389 1,683 SH   SOLE   1,683 0 0
Zentalis Pharmaceuticals Inc Common Stock 98943L107   381 13,492 SH   SOLE   13,492 0 0
Ardelyx Inc Common Stock 039697107   380 112,222 SH   SOLE   112,222 0 0
Exelon Corp Common Stock 30161N101   379 9,304 SH   SOLE   9,304 0 0
Syndax Pharmaceuticals Inc Common Stock 87164F105   377 18,027 SH   SOLE   18,027 0 0
Celldex Therapeutics Inc Common Stock 15117B202   375 11,052 SH   SOLE   11,052 0 0
Kraft Heinz Co/The Common Stock 500754106   374 10,523 SH   SOLE   10,523 0 0
Alibaba Group Holding Ltd ADR 01609W102   374 4,488 SH   DFND   4,488 0 0
Keurig Dr Pepper Inc Common Stock 49271V100   373 11,917 SH   SOLE   11,917 0 0
Paychex Inc Common Stock 704326107   370 3,307 SH   SOLE   3,307 0 0
BioCryst Pharmaceuticals Inc Common Stock 09058V103   369 52,423 SH   SOLE   52,423 0 0
Walmart Inc Common Stock 931142103   368 2,343 SH   SOLE   2,343 0 0
Illumina Inc Common Stock 452327109   365 1,947 SH   SOLE   1,947 0 0
McDonald's Corp Common Stock 580135101   364 1,220 SH   SOLE   1,220 0 0
Danaher Corp Common Stock 235851102   362 1,509 SH   SOLE   1,509 0 0
Old Dominion Freight Line Inc Common Stock 679580100   360 973 SH   SOLE   973 0 0
Align Technology Inc Common Stock 016255101   359 1,015 SH   SOLE   1,015 0 0
Ross Stores Inc Common Stock 778296103   359 3,201 SH   SOLE   3,201 0 0
Sage Therapeutics Inc Common Stock 78667J108   351 7,457 SH   SOLE   7,457 0 0
Workday Inc Common Stock 98138H101   348 1,539 SH   SOLE   1,539 0 0
ImmunoGen Inc Common Stock 45253H101   342 18,133 SH   SOLE   18,133 0 0
CoStar Group Inc Common Stock 22160N109   340 3,823 SH   SOLE   3,823 0 0
SpringWorks Therapeutics Inc Common Stock 85205L107   340 12,950 SH   SOLE   12,950 0 0
Krystal Biotech Inc Common Stock 501147102   335 2,857 SH   SOLE   2,857 0 0
Veracyte Inc Common Stock 92337F107   333 13,085 SH   SOLE   13,085 0 0
Bank of America Corp Common Stock 060505104   332 11,579 SH   SOLE   11,579 0 0
Electronic Arts Inc Common Stock 285512109   329 2,540 SH   SOLE   2,540 0 0
Arcus Biosciences Inc Common Stock 03969F109   328 16,136 SH   SOLE   16,136 0 0
Avidity Biosciences Inc Common Stock 05370A108   327 29,464 SH   SOLE   29,464 0 0
Xcel Energy Inc Common Stock 98389B100   321 5,162 SH   SOLE   5,162 0 0
Bristol-Myers Squibb Co Common Stock 110122108   317 4,953 SH   SOLE   4,953 0 0
AstraZeneca PLC ADR 046353108   316 4,420 SH   SOLE   4,420 0 0
Fastenal Co Common Stock 311900104   316 5,360 SH   SOLE   5,360 0 0
Linde PLC Common Stock G54950103   312 818 SH   SOLE   818 0 0
Viridian Therapeutics Inc Common Stock 92790C104   312 13,122 SH   SOLE   13,122 0 0
Verisk Analytics Inc Common Stock 92345Y106   306 1,355 SH   SOLE   1,355 0 0
Cerevel Therapeutics Holdings Common Stock 15678U128   302 9,501 SH   SOLE   9,501 0 0
Baker Hughes Co Common Stock 05722G100   299 9,471 SH   SOLE   9,471 0 0
Viking Therapeutics Inc Common Stock 92686J106   298 18,403 SH   SOLE   18,403 0 0
Dynavax Technologies Corp Common Stock 268158201   297 22,959 SH   SOLE   22,959 0 0
Dollar Tree Inc Common Stock 256746108   294 2,048 SH   SOLE   2,048 0 0
Medtronic PLC Common Stock G5960L103   294 3,340 SH   SOLE   3,340 0 0
Keysight Technologies Inc Common Stock 49338L103   293 1,747 SH   SOLE   1,747 0 0
Bluebird Bio Inc Common Stock 09609G100   291 88,590 SH   SOLE   88,590 0 0
Warner Bros Discovery Inc Common Stock 934423104   282 22,493 SH   SOLE   22,493 0 0
Constellation Energy Corp Common Stock 21037T109   279 3,046 SH   SOLE   3,046 0 0
Stryker Corp Common Stock 863667101   274 899 SH   SOLE   899 0 0
Walt Disney Co/The Common Stock 254687106   272 3,052 SH   SOLE   3,052 0 0
GLOBALFOUNDRIES Inc Common Stock G39387108   272 4,209 SH   SOLE   4,209 0 0
Gartner Inc Common Stock 366651107   271 775 SH   SOLE   775 0 0
Wells Fargo & Co Common Stock 949746101   267 6,267 SH   SOLE   6,267 0 0
Kymera Therapeutics Inc Common Stock 501575104   265 11,530 SH   SOLE   11,530 0 0
Elevance Health Inc Common Stock 036752103   264 595 SH   SOLE   595 0 0
Corning Inc Common Stock 219350105   262 7,486 SH   SOLE   7,486 0 0
Verizon Communications Inc Common Stock 92343V104   261 7,021 SH   SOLE   7,021 0 0
HP Inc Common Stock 40434L105   260 8,467 SH   SOLE   8,467 0 0
MannKind Corp Common Stock 56400P706   259 63,681 SH   SOLE   63,681 0 0
Immunovant Inc Common Stock 45258J102   257 13,530 SH   SOLE   13,530 0 0
Arcutis Biotherapeutics Inc Common Stock 03969K108   256 26,877 SH   SOLE   26,877 0 0
Editas Medicine Inc Common Stock 28106W103   254 30,923 SH   SOLE   30,923 0 0
Crowdstrike Holdings Inc Common Stock 22788C105   253 1,723 SH   SOLE   1,723 0 0
Philip Morris International In Common Stock 718172109   253 2,593 SH   SOLE   2,593 0 0
NextEra Energy Inc Common Stock 65339F101   251 3,380 SH   SOLE   3,380 0 0
Agios Pharmaceuticals Inc Common Stock 00847X104   249 8,793 SH   SOLE   8,793 0 0
Rocket Pharmaceuticals Inc Common Stock 77313F106   249 12,532 SH   SOLE   12,532 0 0
Invesco QQQ Trust Series 1 ETP 46090E103   246 667 SH   DFND   667 0 0
Vanguard S&P 500 ETF ETP 922908363   246 605 SH   DFND   605 0 0
Arcellx Inc Common Stock 03940C100   245 7,749 SH   SOLE   7,749 0 0
Intercept Pharmaceuticals Inc Common Stock 45845P108   245 22,167 SH   SOLE   22,167 0 0
Myriad Genetics Inc Common Stock 62855J104   245 10,550 SH   SOLE   10,550 0 0
Arcturus Therapeutics Holdings Common Stock 03969T109   244 8,523 SH   SOLE   8,523 0 0
Biohaven Ltd Common Stock G1110E107   244 10,193 SH   SOLE   10,193 0 0
Fate Therapeutics Inc Common Stock 31189P102   244 51,350 SH   SOLE   51,350 0 0
CDW Corp/DE Common Stock 12514G108   243 1,322 SH   SOLE   1,322 0 0
Verve Therapeutics Inc Common Stock 92539P101   242 12,898 SH   SOLE   12,898 0 0
Monolithic Power Systems Inc Common Stock 609839105   239 443 SH   SOLE   443 0 0
RTX Corp Common Stock 75513E101   239 2,441 SH   SOLE   2,441 0 0
Cigna Group/The Common Stock 125523100   238 847 SH   SOLE   847 0 0
CVS Health Corp Common Stock 126650100   238 3,445 SH   SOLE   3,445 0 0
Zoetis Inc Common Stock 98978V103   232 1,346 SH   SOLE   1,346 0 0
Emergent BioSolutions Inc Common Stock 29089Q105   230 31,274 SH   SOLE   31,274 0 0
Rhythm Pharmaceuticals Inc Common Stock 76243J105   230 13,948 SH   SOLE   13,948 0 0
Boston Scientific Corp Common Stock 101137107   229 4,226 SH   SOLE   4,226 0 0
Geron Corp Common Stock 374163103   229 71,235 SH   SOLE   71,235 0 0
Lowe's Cos Inc Common Stock 548661107   225 996 SH   SOLE   996 0 0
Becton Dickinson & Co Common Stock 075887109   224 849 SH   SOLE   849 0 0
eBay Inc Common Stock 278642103   224 5,020 SH   SOLE   5,020 0 0
Walgreens Boots Alliance Inc Common Stock 931427108   224 7,851 SH   SOLE   7,851 0 0
Diamondback Energy Inc Common Stock 25278X109   223 1,701 SH   SOLE   1,701 0 0
S&P Global Inc Common Stock 78409V104   220 548 SH   SOLE   548 0 0
United Parcel Service Inc Common Stock 911312106   217 1,211 SH   SOLE   1,211 0 0
Unity Software Inc Common Stock 91332U101   214 4,927 SH   SOLE   4,927 0 0
Caterpillar Inc Common Stock 149123101   212 861 SH   SOLE   861 0 0
Hewlett Packard Enterprise Co Common Stock 42824C109   212 12,640 SH   SOLE   12,640 0 0
ConocoPhillips Common Stock 20825C104   209 2,021 SH   SOLE   2,021 0 0
HCA Healthcare Inc Common Stock 40412C101   209 690 SH   SOLE   690 0 0
Union Pacific Corp Common Stock 907818108   209 1,019 SH   SOLE   1,019 0 0
Allogene Therapeutics Inc Common Stock 019770106   204 41,061 SH   SOLE   41,061 0 0
Edwards Lifesciences Corp Common Stock 28176E108   201 2,126 SH   SOLE   2,126 0 0
Boeing Co/The Common Stock 097023105   200 945 SH   SOLE   945 0 0
General Electric Co Common Stock 369604301   200 1,819 SH   SOLE   1,819 0 0
VeriSign Inc Common Stock 92343E102   200 886 SH   SOLE   886 0 0
Seres Therapeutics Inc Common Stock 81750R102   199 41,581 SH   SOLE   41,581 0 0
AT&T Inc Common Stock 00206R102   190 11,939 SH   SOLE   11,939 0 0
Day One Biopharmaceuticals Inc Common Stock 23954D109   187 15,641 SH   SOLE   15,641 0 0
Deciphera Pharmaceuticals Inc Common Stock 24344T101   175 12,429 SH   SOLE   12,429 0 0
Scilex Holding Co Common Stock 80880W106   175 31,431 SH   SOLE   31,431 0 0
CareDx Inc Common Stock 14167L103   157 18,437 SH   SOLE   18,437 0 0
Avid Bioservices Inc Common Stock 05368M106   154 10,990 SH   SOLE   10,990 0 0
Anavex Life Sciences Corp Common Stock 032797300   153 18,853 SH   SOLE   18,853 0 0
ADMA Biologics Inc Common Stock 000899104   142 38,613 SH   SOLE   38,613 0 0
Sirius XM Holdings Inc Common Stock 82968B103   135 29,726 SH   SOLE   29,726 0 0
Cogent Biosciences Inc Common Stock 19240Q201   131 11,088 SH   SOLE   11,088 0 0
Recursion Pharmaceuticals Inc Common Stock 75629V104   129 17,229 SH   SOLE   17,229 0 0
2seventy bio Inc Common Stock 901384107   126 12,420 SH   SOLE   12,420 0 0
Agenus Inc Common Stock 00847G705   124 77,312 SH   SOLE   77,312 0 0
uniQure NV Common Stock N90064101   122 10,653 SH   SOLE   10,653 0 0
Viatris Inc Common Stock 92556V106   120 12,016 SH   SOLE   12,016 0 0
Aldeyra Therapeutics Inc Common Stock 01438T106   114 13,612 SH   SOLE   13,612 0 0
Kura Oncology Inc Common Stock 50127T109   112 10,628 SH   SOLE   10,628 0 0
Sana Biotechnology Inc Common Stock 799566104   108 18,054 SH   SOLE   18,054 0 0
Lucid Group Inc Common Stock 549498103   97 14,095 SH   SOLE   14,095 0 0
Point Biopharma Global Inc Common Stock 730541109   95 10,524 SH   SOLE   10,524 0 0
Allakos Inc Common Stock 01671P100   83 18,996 SH   SOLE   18,996 0 0
Vanda Pharmaceuticals Inc Common Stock 921659108   78 11,832 SH   SOLE   11,832 0 0
Bioxcel Therapeutics Inc Common Stock 09075P105   71 10,628 SH   SOLE   10,628 0 0
EQRx Inc Common Stock 26886C107   62 33,322 SH   SOLE   33,322 0 0
Mersana Therapeutics Inc Common Stock 59045L106   60 18,105 SH   SOLE   18,105 0 0
Lyell Immunopharma Inc Common Stock 55083R104   56 17,491 SH   SOLE   17,491 0 0
FibroGen Inc Common Stock 31572Q808   53 19,515 SH   SOLE   19,515 0 0