144 0001676170 XXXXXXXX LIVE 0001842295 Maze Therapeutics, Inc. 001-42490 171 OYSTER POINT BOULEVARD, SUITE 300 SOUTH SAN FRANCISCO CA 94080 6508505070 Coloma Jason V Officer Common UBS Financial Services Inc.

Eleven Madison Avenue 4th Floor New York NY 10010

34502 895326.90 55345261 05/15/2026 Nasdaq Common 09/22/2021 Gift Jason Coloma Y 11/01/2018 2594 09/22/2021 NA Common 09/22/2021 Gift Jason Coloma Y 06/24/2019 31908 09/22/2021 NA Y 2,594 shares for this filing were sold under The Coloma 2021 Irrevocable Trust DTD 09/20/2021 and 31,908 shares were sold under Coloma Family Trust DTD 06/27/2016 05/15/2026 02/10/2026 /s/ UBS Financial Services Inc., as attorney-in-fact for Jason Coloma as trustee