X0206 3 2021-01-27 0 0001610950 Syneos Health, Inc. SYNH 0001841663 Kralowetz Donna Hildebrand C/O SYNEOS HEALTH, INC. 1030 SYNC STREET MORRISVILLE NC 27560 0 1 0 0 SVP, Chief Accounting Officer Class A Common Stock 6321 D Includes (i) 840 shares of restricted stock units ("RSUs") that vest on June 17, 2021; (ii) 839 RSUs that vest on June 17, 2022; (iii) 1,613 RSUs that vest on January 15, 2022; (iv) 1,612 RSUs that vest on January 15, 2023; and (v) 1,055 RSUs that vest on January 15, 2024, all subject to continued employment. /s/ Sara Epstein, Attorney-in-Fact 2021-02-04