SCHEDULE 13G 0001766853 XXXXXXXX LIVE Common stock, par value $0.0001 per share 06/25/2025 0001841387 Candel Therapeutics, Inc. 137404109 117 KENDRICK STREET SUITE 450 NEEDHAM MA 02494 Rule 13d-1(c) ACORN BIOVENTURES, L.P. b DE 0.00 1083818.00 0.00 1083818.00 1083818.00 2.2 PN ACORN BIOVENTURES 2, L.P. b DE 0.00 1496699.00 0.00 1496699.00 1496699.00 3.0 PN ACORN CAPITAL ADVISORS GP, LLC b DE 0.00 1083818.00 0.00 1083818.00 1083818.00 2.2 OO Acorn Capital Advisors GP2, LLC b DE 0.00 1496699.00 0.00 1496699.00 1496699.00 3.0 OO Anders Hove b X1 0.00 2580517.00 0.00 2580517.00 2580517.00 5.2 IN Candel Therapeutics, Inc. 117 KENDRICK STREET, SUITE 450, NEEDHAM, MASSACHUSETTS, 02494. Acorn Bioventures, L.P. Acorn Bioventures 2, L.P. Acorn Capital Advisors GP, LLC Acorn Capital Advisors GP2, LLC Anders Hove 420 Lexington Avenue, Suite 2626, New York, NY 10170 Acorn Bioventures, L.P. and Acorn Bioventures 2, L.P. are both a Delaware limited partnerships. Acorn Capital Advisors GP, LLC and Acorn Capital Advisors GP 2, LLC are both Delaware limited liability companies. Anders Hove is a citizen of the United States of America. Y The information required by Items 4(a) - (c) is set forth in Rows (5) - (11) of the cover page for each Reporting Person hereto and is incorporated herein by reference for each Reporting Person. The percentages set forth herein are calculated based upon 50,102,679 shares of Common Stock outstanding as of May 5, 2025 as reported by the issuer's first quarter 2025 10Q filing. 0 Acorn Capital Advisors GP, LLC is the General Partner of Acorn Bioventures, L.P. and may be deemed to beneficially own the shares of Common Stock beneficially owned by Acorn Bioventures, L.P. Acorn Capital Advisors GP 2, LLC is the general partner of Acorn Bioventures 2, L.P. and may be deemed to beneficially own the shares of Common Stock beneficially owned by Acorn Bioventures 2, L.P. 0 Anders Hove, in his capacity as manager of each of Acorn Capital Advisors GP, LLC and Acorn Capital Advisors GP 2, LLC, may be deemed to beneficially own the shares beneficially owned by each of Acorn Capital Advisors GP, LLC and Acorn Capital Advisors GP 2, LLC. Y N Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11. ACORN BIOVENTURES, L.P. Anders Hove 06/30/2025 ACORN BIOVENTURES 2, L.P. Anders Hove 06/30/2025 ACORN CAPITAL ADVISORS GP, LLC Anders Hove 06/30/2025 Acorn Capital Advisors GP2, LLC Anders Hove 06/30/2025 Anders Hove Anders Hove 06/30/2025