X0306 4 2022-08-08 0 0001841387 Candel Therapeutics, Inc. CADL 0001242215 PAPA JOSEPH C C/O CANDEL THERAPEUTICS, INC. 117 KENDRICK ST., SUITE 450 NEEDHAM MA 02494 1 0 0 0 Stock Option (Right to Buy) 3.38 2022-08-08 4 A 0 28480 0.00 A 2032-08-08 Common Stock 28480 28480 D 33% of the shares underlying this option shall vest and become exercisable on August 8, 2023, with the remainder vesting in two (2) equal annual installments thereafter, subject to the Reporting Person's continued service on each such vesting date. /s/ John Canepa, as Attorney-In-Fact for Joseph Papa 2022-08-10