Income Taxes - Schedule of Effective Income Tax Rate Reconciliation (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Income (Loss), Including Portion Attributable to Noncontrolling Interest, before Tax [Abstract]
Income (Loss) Attributable to Parent, before Tax	$ (136,601)	$ (101,813)
German statutory rate	30.18%	30.18%
Expected income tax expense (benefit)	$ (41,220)	$ (30,722)
US state income taxes, net of US federal tax benefit and valuation allowance	132	74
International tax rate differential	4,222	2,304
Effect of taxes not provided on outside basis differences in consolidated subsidiaries regarding: fair value adjustments	0	(247)
Effect of taxes not provided on outside basis differences in consolidated subsidiaries regarding: IPR&D charges and acquisition adjustments	3,251	2,164
Effect of Australian R&D tax credit incentives	(3)	240
Effect of taxes not provided on outside basis differences in investments regarding: fair value adjustments	2,934	(6,175)
Effect of statutory to US GAAP accounting adjustments	(10,409)
Compensation Expenses not deductible under IRC Sections	1,690
Expenses not deductible for tax purposes	612	(55)
Effect of German participation exemption on outside basis differences		(5)
Effect of non-deductible compensation in respect of convertible notes		18,558
Effect of conversion of convertible notes		4,846
Effect of share-based compensation expense	192
Other	(657)	(1)
Change in valuation allowance	35,267	9,324
Total income tax expense:	$ (3,989)	$ 305
Effective income tax rate:	2.92%	(0.30%)
Germany
Income (Loss), Including Portion Attributable to Noncontrolling Interest, before Tax [Abstract]
Income (Loss) Attributable to Parent, before Tax	$ (89,061)	$ (75,966)
Overseas
Income (Loss), Including Portion Attributable to Noncontrolling Interest, before Tax [Abstract]
Income (Loss) Attributable to Parent, before Tax	$ (47,540)	$ (25,847)