Variable Interest Entities and a Voting Interest Entity - Schedule of Roll Forward of the Redeemable Noncontrolling Interests Balance (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Redeemable Noncontrolling Interest [Line Items]
Opening balance	$ 0	$ 142
Issuance of redeemable noncontrolling interests	2,555
Net loss attributable to redeemable noncontrolling interests - common	(2,555)
Net loss attributable to redeemable noncontrolling interests - preferred		(142)
Closing balance	0	0
Kures [Member]
Redeemable Noncontrolling Interest [Line Items]
Opening balance	0	142
Issuance of redeemable noncontrolling interests	0
Net loss attributable to redeemable noncontrolling interests - common	0
Net loss attributable to redeemable noncontrolling interests - preferred		(142)
Closing balance	0	0
Neuronasal Inc [Member]
Redeemable Noncontrolling Interest [Line Items]
Opening balance	0	0
Issuance of redeemable noncontrolling interests	2,555
Net loss attributable to redeemable noncontrolling interests - common	(2,555)
Net loss attributable to redeemable noncontrolling interests - preferred		0
Closing balance	$ 0	$ 0