UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 6-K

REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934

For the month of May 2025.

____________________________________

Commission File Number: 001-40627

SOPHiA GENETICS SA

(Exact name of registrant as specified in its charter)

La Pièce 12

CH-1180 Rolle

Switzerland

(Address of principal executive office)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:

Form 20-F x Form 40-F

SIGNATURE

SOPHiA GENETICS SA (the “Company”) provided to its shareholders an invitation to the Company’s annual general meeting of shareholders. The annual general meeting of shareholders is expected to take place on June 18, 2025 at 8:00 a.m. EDT / 2:00 p.m. CEST at the Company’s office at La Pièce 12, 1180 Rolle/VD, Switzerland.

		SOPHiA GENETICS SA
Date:	May 8, 2025
		By:	/s/ Daan van Well
		Name:	Daan van Well
		Title:	Chief Legal and Regulatory Officer

EXHIBIT INDEX

Exhibit No.	Description
99.1	Invitation to the Annual General Meeting 2025
99.2	Shareholder Annual General Meeting Notice 2025
99.3	Annual General Meeting Proxy Card (Broker) 2025
99.4	Annual General Meeting Proxy Card (Common Shareholder) 2025