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Income Tax - Reconciliation of Expected Tax Expense to Tax Expense Report in Statement of Loss (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Major Components Of Tax Expense Income [Abstract]      
Loss before tax $ (73,507) $ (41,225) $ (33,629)
Tax at Swiss statutory rate 9,907 5,541 4,519
Effect of tax rates in foreign jurisdictions (218) (177) 568
Unrecognized deferred tax assets (9,077) (3,276) (5,110)
Income not subject to tax (expense not deductible for tax purposes) (805) 41 (1)
Uncertain tax positions (110) (74) (76)
Other 135 (169) (62)
Total income tax (expense) benefit $ (168) $ 1,886 $ (162)