SCHEDULE 13G/A 0001702178 XXXXXXXX LIVE 3 Ordinary Shares, CHF 0.05 per share 12/31/2025 0001840706 Sophia Genetics SA H82027105 La Piece 12 Rolle V8 CH-1180 Rule 13d-1(d) Balderton Capital VI, S.L.P. b N4 0 3301240 0 3301240 3301240 N 4.9 PN All shares are held of record by BCVI (as defined in Item 2(a) of the Original Schedule 13G (as defined below)). BCVI Sarl (as defined in Item 2(a) of the Original Schedule 13G) is the managing general partner of BCVI and may be deemed to have voting, investment and dispositive power with respect to these securities. The Managers (as defined in Item 4 of the Original Schedule 13G) are the managers of BCVI Sarl and may each be deemed to share voting, investment and dispositive power with respect to these securities. The percentage in Row 11 is based upon 67,579,560 of the Issuer's Ordinary Shares outstanding as of June 30, 2025, as reported in the Issuer's prospectus on Form 424(b)(5) filed with the United States Securities and Exchange Commission (the "Commission") on August 15, 2025 (the "Prospectus"). Sophia Genetics SA La Piece 12, Rolle, Switzerland, CH-1180 This Amendment No. 3 (this "Amendment No. 3") is being filed to amend and restate the Schedule 13G originally filed by the Reporting Persons with the Commission on February 10, 2022, as amended by Amendment No. 1 filed with the Commission on February 13, 2024 and Amendment No. 2 filed with the Commission on February 20, 2024 (collectively, the "Original Schedule 13G"). Only those items that are hereby reported are amended; all other items reported in the Original Schedule 13G remain unchanged. Information given in response to each item shall be deemed incorporated by reference in all other items, as applicable. Capitalized terms not defined in this Amendment No. 3 have the meanings ascribed to them in the Original Schedule 13G. BCVI Sarl is the general partner of BCVI, and its capacity as such was included as a Reporting Person in the Original Schedule 13G. A cover page for BCVI Sarl is not included in this Amendment No. 3 because BCVI Sarl does not have codes for the EDGAR filing system at this time. Y See Row 9 of the cover page for each Reporting Person and the corresponding comments.* See Row 11 of the cover page for each Reporting Person and the corresponding comments.* See Row 5 of the cover page for each Reporting Person and the corresponding comments.* See Row 6 of the cover page for each Reporting Person and the corresponding comments.* See Row 7 of the cover page for each Reporting Person and the corresponding comments.* See Row 8 of the cover page for each Reporting Person and the corresponding comments.* *Except to the extent of his, her or its pecuniary interest therein, each Reporting Person disclaims beneficial ownership of such Ordinary Shares, except for the shares, if any, such Reporting Person holds of record. N Y Y Y Y Y Y Balderton Capital VI, S.L.P. /s/ Petr Klimo 02/11/2026