Condensed Consolidated Statement of Convertible Preferred Stock and Stockholders' Equity (Deficit) - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-In Capital	Accumulated Other Comprehensive Loss	Accumulated Deficit
Beginning Balance at Dec. 31, 2021	$ 357,352	$ 49	$ 544,381	$ (228)	$ (186,850)
Beginning Balance (in shares) at Dec. 31, 2021		48,511,735
Exercise of stock options	505		505
Exercise of stock options (in shares)		143,506
Unrealized loss on available-for-sale securities	(504)			(504)
Stock-based compensation	4,203		4,203
Net loss	(30,166)				(30,166)
Ending Balance at Mar. 31, 2022	331,390	$ 49	549,089	(732)	(217,016)
Ending balance (in shares) at Mar. 31, 2022		48,655,241
Beginning Balance at Dec. 31, 2021	357,352	$ 49	544,381	(228)	(186,850)
Beginning Balance (in shares) at Dec. 31, 2021		48,511,735
Net loss	(71,112)
Ending Balance at Jun. 30, 2022	296,333	$ 49	555,184	(938)	(257,962)
Ending balance (in shares) at Jun. 30, 2022		48,709,652
Beginning Balance at Mar. 31, 2022	331,390	$ 49	549,089	(732)	(217,016)
Beginning Balance (in shares) at Mar. 31, 2022		48,655,241
Exercise of stock options	120		120
Exercise of stock options (in shares)		29,193
Issuance of common stock under Employee Stock Purchase Plan, shares		25,218
Issuance of common stock under Employee Stock Purchase Plan	325		325
Unrealized loss on available-for-sale securities	(206)			(206)
Stock-based compensation	5,650		5,650
Net loss	(40,946)				(40,946)
Ending Balance at Jun. 30, 2022	296,333	$ 49	555,184	(938)	(257,962)
Ending balance (in shares) at Jun. 30, 2022		48,709,652
Beginning Balance at Dec. 31, 2022	$ 550,932	$ 62	895,801	(694)	(344,237)
Beginning Balance (in shares) at Dec. 31, 2022	61,730,816	61,730,816
Exercise of stock options	$ 116		116
Exercise of stock options (in shares)		29,010
Unrealized loss on available-for-sale securities	457			457
Stock-based compensation	8,024		8,024
Issuance of common stock from At-the-Market offering, net of issuance costs, shares		103,184
Issuance of common stock from At-the-Market offering, net of issuance costs	1,922		1,922
Net loss	(51,975)				(51,975)
Ending Balance at Mar. 31, 2023	509,476	$ 62	905,863	(237)	(396,212)
Ending balance (in shares) at Mar. 31, 2023		61,863,010
Beginning Balance at Dec. 31, 2022	$ 550,932	$ 62	895,801	(694)	(344,237)
Beginning Balance (in shares) at Dec. 31, 2022	61,730,816	61,730,816
Exercise of stock options (in shares)	127,608
Net loss	$ (105,958)
Ending Balance at Jun. 30, 2023	$ 465,222	$ 62	916,109	(754)	(450,195)
Ending balance (in shares) at Jun. 30, 2023	62,064,279	62,064,279
Beginning Balance at Mar. 31, 2023	$ 509,476	$ 62	905,863	(237)	(396,212)
Beginning Balance (in shares) at Mar. 31, 2023		61,863,010
Vesting of restricted stock units (in shares)		50,537
Exercise of stock options	548		548
Exercise of stock options (in shares)		98,598
Issuance of common stock under Employee Stock Purchase Plan, shares		52,134
Issuance of common stock under Employee Stock Purchase Plan	685		685
Unrealized loss on available-for-sale securities	(517)			(517)
Stock-based compensation	9,013		9,013
Net loss	(53,983)				(53,983)
Ending Balance at Jun. 30, 2023	$ 465,222	$ 62	$ 916,109	$ (754)	$ (450,195)
Ending balance (in shares) at Jun. 30, 2023	62,064,279	62,064,279