Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity (Deficit) - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-In Capital	Accumulated Other Comprehensive Income	Accumulated Deficit	Preferred Stock
Beginning balance at Dec. 31, 2019	$ (19,553)	$ 2	$ 1,268	$ 9	$ (20,832)	$ 25,480
Beginning balance (in shares) at Dec. 31, 2019		1,854,438				51,421,404
Issuance of Series A convertible preferred stock and settlement of tranche right liability, net of issuance costs						$ 36,792
Issuance of Series A convertible preferred stock and settlement of tranche right liability, net of issuance costs (in shares)						49,749,167
Issuance of Series A-2 convertible preferred stock, net of issuance costs of $112						$ 62,888
Issuance of Series A-2 convertible preferred stock, net of issuance costs (in shares)						78,348,461
Additional issuances of common stock to licensor institutions	487		487
Additional issuances of common stock to licensor institutions (in shares)		187,867
Vesting of restricted common stock	1	$ 1
Vesting of restricted common stock (in shares)		537,635
Exercise of stock options	11		11
Exercise of stock options (in shares)		5,849
Unrealized loss on available-for-sale securities	(1)			(1)
Stock-based compensation	850		850
Net loss	(45,704)				(45,704)
Ending balance at Dec. 31, 2020	(63,909)	$ 3	2,616	8	(66,536)	$ 125,160
Ending balance (in shares) at Dec. 31, 2020		2,585,789				179,519,032
Issuance of Series B convertible preferred stock, net of issuance costs of $241						$ 93,759
Issuance of Series B convertible preferred stock, net of issuance costs (in shares)						77,163,022
Conversion of convertible preferred stock to common stock upon closing of initial public offering	218,919	$ 28	218,891			$ (218,919)
Conversion of convertible preferred stock to common stock upon closing of initial public offering (in shares)		27,720,923				(256,682,054)
Issuance of common stock from initial public offering, net of issuance costs of $25,098	281,584	$ 16	281,568
Issuance of common stock from initial public offering, net of issuance costs of (in shares)		16,141,157
Issuances of common stock to licensor institutions	32,490	$ 1	32,489
Issuances of common stock to licensor institutions (in shares)		878,098
Vesting of restricted common stock (in shares)		537,633
Exercise of stock options	966	$ 1	965
Exercise of stock options (in shares)		599,838
Purchase of common stock under ESPP	780		780
Purchase of common stock under ESPP(shares)		48,297
Unrealized loss on available-for-sale securities	(236)			(236)
Stock-based compensation	7,072		7,072
Net loss	(120,314)				(120,314)
Ending balance at Dec. 31, 2021	$ 357,352	$ 49	544,381	(228)	(186,850)
Ending balance (in shares) at Dec. 31, 2021	48,511,735	48,511,735
Issuance of common stock from initial public offering, net of issuance costs of $25,098	$ 242,826	$ 10	242,816
Issuance of common stock from initial public offering, net of issuance costs of (in shares)		9,583,334
Issuances of common stock to licensor institutions	39,986	$ 2	39,984
Issuances of common stock to licensor institutions (in shares)		1,519,756
Issuance of common stock from At-the-Market offering, net of issuance costs of , (In Shares)		1,280,168
Issuance of common stock from At-the-Market offering, net of issuance costs	42,900	$ 1	42,899
Vesting of restricted common stock (in shares)		6,375
Exercise of stock options	$ 2,175		2,175
Exercise of stock options (in shares)	743,638	743,638
Purchase of common stock under ESPP	$ 1,069		1,069
Purchase of common stock under ESPP(shares)		85,810
Unrealized loss on available-for-sale securities	(466)			(466)
Stock-based compensation	22,477		22,477
Net loss	(157,387)				(157,387)
Ending balance at Dec. 31, 2022	$ 550,932	$ 62	$ 895,801	$ (694)	$ (344,237)
Ending balance (in shares) at Dec. 31, 2022	61,730,816	61,730,816