Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Income Statement [Abstract]
Collaborations revenue	$ 1,941	$ 0	$ 0
Operating expenses:
Research and development	130,095	68,202	35,371
General and administrative	37,533	18,865	5,256
Total operating expenses	167,628	87,067	40,627
Loss from operations	(165,687)	(87,067)	(40,627)
Other income (expense):
Change in fair value of preferred stock tranche liability	0	0	2,507
Change in fair value of antidilution rights liability	0	(25,574)	(5,359)
Change in fair value of success payment liability	1,486	(7,815)	(2,387)
Interest and other income, net	6,867	142	162
Total other expense, net	8,353	(33,247)	(5,077)
Loss before provision for income taxes	(157,334)	(120,314)	(45,704)
Provision for income taxes	53	0	0
Net loss	$ (157,387)	$ (120,314)	$ (45,704)
Net loss per common share attributable to common stockholders, basic	$ (2.91)	$ (4.48)	$ (20.31)
Net loss per common share attributable to common stockholders, diluted	$ (2.91)	$ (4.48)	$ (20.31)
Weighted-average common shares used in net loss per share attributable to common stockholders, basic	54,023,653	26,872,036	2,250,093
Weighted-average common shares used in net loss per share attributable to common stockholders, diluted	54,023,653	26,872,036	2,250,093
Comprehensive Loss:
Net loss	$ (157,387)	$ (120,314)	$ (45,704)
Other comprehensive loss:
Unrealized loss on marketable securities	(466)	(236)	(1)
Comprehensive loss	$ (157,853)	$ (120,550)	$ (45,705)