Net Loss Per Share Attributable to Common Stockholders

12 Months Ended

Dec. 31, 2022

Net Loss Per Share Attributable to Common Stockholders

12. Net loss per share attributable to common stockholders

The following table summarizes the computation of basic and diluted net loss per share attributable to common stockholders of the Company:


	Year ended December 31,
(in thousands, except share and per share amounts)	2022			2021			2020
Numerator:
Net loss attributable to common stockholders	$	(157,387	)	$	(120,314	)	$	(45,704	)
Denominator:
Weighted average number of common shares, basic and diluted		54,023,653			26,872,036			2,250,093
Net loss per common share attributable to common stockholders, basic and diluted	$	(2.91	)	$	(4.48	)	$	(20.31	)

The Company’s potential dilutive securities, which include convertible preferred stock, unvested restricted stock, unvested restricted stock units, and common stock options, have been excluded from the computation of diluted net loss per share as the effects would be anti-dilutive. Therefore, the weighted average number of common shares outstanding used to calculate both basic and diluted net loss per share attributable to common stockholders is the same. The Company excluded the following potential common shares, presented based on amounts outstanding at period end, from the computation of diluted net loss per share attributable to common stockholders for the period indicated because including them would have had an anti-dilutive effect:


	Year ended December 31,
	2022		2021		2020
Convertible preferred stock		—		—		19,387,544
Unvested restricted stock		—		—		537,633
Unvested restricted stock units		677,825		32,000		—
Outstanding options to purchase common stock		7,612,826		6,119,295		3,888,823
Total		8,290,651		6,151,295		23,814,000

As part of the license agreements with Harvard and Broad, the Company is required to make success payments. The Company may elect to make these payments by issuing shares of the Company's common stock. As of December 31, 2022, an aggregate of $6.3 million was earned relating to these success payments, which the Company settled in cash in November 2021. No success payments were triggered or paid during the year ended December 31, 2022.