Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Cash flows from operating activities:
Net loss	$ (71,112)	$ (66,228)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	1,162	651
Non-cash lease expense	999	865
Amortization of premium on marketable securities	1,231	356
Stock-based compensation	9,853	2,021
Change in fair value of antidilution rights	0	25,574
Change in fair value of success payments liabilities	(2,615)	9,654
Changes in operating assets and liabilities:
Prepaid expenses and other assets	(2,894)	(159)
Accounts payable	(1,017)	1,283
Accrued expenses and other liabilities	5,176	(1,584)
Operating lease liabilities	(1,048)	(915)
Net cash used in operating activities	(60,265)	(28,482)
Cash flows from investing activities:
Purchases of property and equipment	(5,627)	(2,376)
Purchases of marketable securities	(74,249)	(11,176)
Maturities of marketable securities	147,750	43,755
Net cash provided by investing activities	67,874	30,203
Cash flows from financing activities:
Proceeds from issuance of Series B convertible preferred stock, net	0	93,759
Proceeds from initial public offering, net of underwriting discount	0	285,214
Payment of initial public offering costs	0	(2,765)
Proceeds from exercise of stock options	625	524
Issuance of shares through employee stock purchase plan	325	0
Net cash provided by financing activities	950	376,732
Increase in cash, cash equivalents and restricted cash	8,559	378,453
Cash, cash equivalents and restricted cash—beginning of period	69,567	9,456
Cash, cash equivalents and restricted cash—end of period	78,126	387,909
Supplemental disclosure of noncash investing and financing activities:
Property and equipment additions included in accounts payable and accrued expenses	1,169	794
Initial public offering costs included in accounts payable and accrued liabilities	0	865
Conversion of convertible preferred stock to common stock upon closing of initial public offering		218,919
Settlement of antidilution rights liability by issuing common stock	$ 0	$ 32,490