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License Agreements - Additional Information (Details) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended 10 Months Ended 12 Months Ended
Oct. 31, 2021
Apr. 30, 2019
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Oct. 31, 2020
Dec. 31, 2020
Dec. 31, 2019
Mar. 31, 2022
Dec. 31, 2021
Sep. 30, 2021
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Research and development expenses     $ 33,125,000 $ 13,423,000 $ 57,614,000 $ 24,768,000            
Common stock shares issued     48,709,652   48,709,652           48,511,735  
Issuance of common stock       281,584,000   (32,490,000)            
Issuance of common stock, value     $ 49,000   $ 49,000           $ 49,000  
Broad License Agreement                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Common stock shares issued     276,075   276,075              
Issuance of common stock         $ 300,000              
Preferred stock financing partially satisfied                 $ 100,000      
Preferred stock financing were fully satisfied               $ 500,000        
Common stock issued for partly satisfying preferred stock financing                 $ 121,411      
Common stock issued for fully satisfying preferred stock financing               187,867        
Payment of milestone development         46,200,000              
Payment of sales based milestone         108,000,000              
Harvard and Board                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Success payment liability                   $ 300,000   $ 6,300,000
Beam License Agreement                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Research and development expenses     $ 0 0 0 0            
Common stock shares issued   276,075                    
Issuance of common stock   $ 300,000                    
Payment of milestone development   11,300,000                    
Payment of sales based milestone   15,000,000.0                    
Payment Received for License Agreement Reimbursement of Costs Incurred           200,000            
Beam License Agreement | Non-US                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Payment of milestone development   5,600,000                    
Payment of sales based milestone   $ 7,500,000                    
Beam License Agreement | NZ                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Payment of sales based milestone         200,000              
Acuitas Agreements                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Research and development expenses     100,000 300,000 100,000 600,000            
sell | Beam License Agreement                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Research and development expenses     $ 0 $ 0 0 $ 0            
License Agreement                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Non-Refundable Upfront License Fees Paid $ 800,000                      
Non Refundable Upfront License Fee         2,800,000   $ 2,000,000.0          
Clinical And Regulatory Milestone         9,800,000              
Sales Based Milestone         9,500,000              
Milestone related expenses $ 10,000,000.0       0              
License Agreement | Broad License Agreement                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Non-Refundable Upfront License Fees Paid         $ 300,000              
Antidilution Rights | Broad License Agreement                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Common stock shares issued     878,098   878,098              
Issuance of common stock, value     $ 32,500,000   $ 32,500,000