License Agreements - Additional Information (Details) - USD ($)	1 Months Ended		3 Months Ended		10 Months Ended	12 Months Ended
	Oct. 31, 2021	Apr. 30, 2019	Mar. 31, 2022	Mar. 31, 2021	Oct. 31, 2020	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2021	Sep. 30, 2021
Research And Development Arrangement Contract To Perform For Others [Line Items]
Research and development expenses			$ 24,490,000	$ 11,345,000
Common stock shares issued			48,655,241					48,511,735
Issuance of common stock, value			$ 49,000					$ 49,000
Broad License Agreement
Research And Development Arrangement Contract To Perform For Others [Line Items]
Common stock shares issued			276,075
Issuance of common stock			$ 300,000
Preferred stock financing partially satisfied							$ 100,000
Preferred stock financing were fully satisfied						$ 500,000
Common stock issued for partly satisfying preferred stock financing							$ 121,411
Common stock issued for fully satisfying preferred stock financing						187,867
Payment of milestone development			46,200,000
Payment of sales based milestone			108,000,000
Harvard and Board
Research And Development Arrangement Contract To Perform For Others [Line Items]
Success payment liability			300,000						$ 6,300,000
Beam License Agreement
Research And Development Arrangement Contract To Perform For Others [Line Items]
Research and development expenses			0	0
Common stock shares issued		276,075
Issuance of common stock		$ 300,000
Payment of milestone development		11,300,000
Payment of sales based milestone		15,000,000.0
Reimbursement received related to reduction to research and development expense				200,000
Milestone related expenses			0
Beam License Agreement | Non-US
Research And Development Arrangement Contract To Perform For Others [Line Items]
Payment of milestone development		5,600,000
Payment of sales based milestone		$ 7,500,000
Acuitas Agreements
Research And Development Arrangement Contract To Perform For Others [Line Items]
Research and development expenses			100,000	$ 300,000
License Agreement
Research And Development Arrangement Contract To Perform For Others [Line Items]
Non Refundable Upfront License Fee					$ 2,000,000.0
Clinical And Regulatory Milestone			9,800,000
Sales Based Milestone			9,500,000
Milestone related expenses	$ 10,000,000.0		0
License Agreement | Broad License Agreement
Research And Development Arrangement Contract To Perform For Others [Line Items]
Non-Refundable Upfront License Fees Paid			$ 300,000
Antidilution Rights | Broad License Agreement
Research And Development Arrangement Contract To Perform For Others [Line Items]
Common stock shares issued			878,098
Issuance of common stock, value			$ 32,500,000