Segment Reporting - Summary of Research and Development Expenses (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
External costs
Other clinical related expenses	$ 1,396	$ 2,345	$ 4,726	$ 11,160
Preclinical activities related expenses	1,191	1,707	4,741	8,296
Expenses related to manufacturing of clinical and research material	1,420	884	3,689	5,014
Other external costs	1,429	4,065	5,900	7,886
Internal costs:
Personnel-related expenses (including stock-based compensation)	3,822	8,579	17,342	27,584
Facilities and other allocated expenses	1,200	1,926	5,378	6,109
Total research and development expenses	14,401	27,244	53,864	92,845
COVALENT - 101
External costs
Clinical research organization expenses	241	925	2,168	1,507
COVALENT - 102
External costs
Clinical research organization expenses	668	(54)	1,140	420
COVALENT - 103
External costs
Clinical research organization expenses	1,146	823	2,744	2,403
COVALENT - 111
External costs
Clinical research organization expenses	1,032	5,152	4,367	18,311
COVALENT - 112
External costs
Clinical research organization expenses	601	$ 892	1,414	$ 4,155
GLP - 131
External costs
Clinical research organization expenses	$ 255		$ 255