<?xml version="1.0" encoding="UTF-8"?><!-- Generated by CompSci Transform (tm) - http://www.compsciresources.com --><!-- Created: Thu Feb 12 21:02:40 UTC 2026 --><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:common="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001858703</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <securitiesClassTitle>Common Stock, $0.0001 par value per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>12/31/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001840439</issuerCik>
        <issuerName>Biomea Fusion, Inc.</issuerName>
        <issuerCusip>09077A106</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <common:street1>1599 INDUSTRIAL ROAD</common:street1>
          <common:city>SAN CARLOS</common:city>
          <common:stateOrCountry>CA</common:stateOrCountry>
          <common:zipCode>94070</common:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(b)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Blue Owl Capital Holdings LP</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>4451219</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>4451219</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>4451219</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>5.92</classPercent>
      <typeOfReportingPerson>PN</typeOfReportingPerson>
      <comments>The reported securities represent 4,451,219 shares of Common Stock issuable upon exercise of warrants to each acquire one share of Common Stock ("Warrants"). The percentage of class is calculated based upon 70,703,639 shares of Common Stock outstanding as of October 31, 2025, as reported on the Issuer's 10-Q filed with the Securities and Exchange Commission on November 4, 2025, as increased by the 4,451,219 shares of Common Stock issuable upon exercise of the Warrants.</comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Biomea Fusion, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>1599 INDUSTRIAL ROAD SAN CARLOS, CA, 94070</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>This statement is filed by the Blue Owl Capital Holdings LP, referred to herein as the "Reporting Person."</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>399 Park Avenue
New York, New York 10022</principalBusinessOfficeOrResidenceAddress>
        <citizenship>See response to Item 4 on the cover page.</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>N</notApplicableFlag>
        <typeOfPersonFiling>IA</typeOfPersonFiling>
      </item3>
      <item4>
        <amountBeneficiallyOwned>See response to Item 9 on the cover page.

The filing of this statement shall not be deemed an admission by any of the Reporting Persons, of beneficial ownership of the reported securities for purposes of Section 13(d) or Section 13(g) or for any other purpose.</amountBeneficiallyOwned>
        <classPercent>See response to Item 11 on the cover page.</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>See response to Item 5 on the cover page.</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>See response to Item 6 on the cover page.</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>See response to Item 7 on the cover page.</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>See response to Item 8 on the cover page.</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>Blue Owl Capital Holdings LP</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Karen Hager</signature>
        <title>Karen Hager/Chief Compliance Officer</title>
        <date>02/12/2026</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>
