Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Cash flows from operating activities
Net loss	$ (138,426)	$ (117,255)	$ (81,828)
Adjustments to reconcile net loss to net cash used in operating activities
Depreciation expense	1,748	1,515	691
Non-cash operating lease expense	2,838	2,686	571
Stock-based compensation expense	19,094	14,131	10,336
Net amortization of premiums and accretion of discounts on investments		1	144
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	(7,738)	2,478	(1,725)
Other assets	4,884	(2,358)	(1,915)
Accounts payable	6,088	2,562	2,960
Accrued expenses and other current liabilities	(6,881)	1,886	8,914
Operating lease liabilities	(1,501)	(2,238)	(565)
Net cash used in operating activities	(119,894)	(96,592)	(62,417)
Cash flows from investing activities
Purchase of property and equipment	(362)	(3,370)	(1,030)
Maturities of investments		1,150	28,371
Net cash (used in) provided by investing activities	(362)	(2,220)	27,341
Cash flows from financing activities
Proceeds from issuance of common stock, net of offering costs		161,803
Proceeds from stock options exercised and purchases under the employee stock purchase plan	1,668	1,995	1,239
Net cash provided by financing activities	1,668	163,798	1,239
Net (decrease) increase in cash, cash equivalents, and restricted cash	(118,588)	64,986	(33,837)
Cash, cash equivalents, and restricted cash at the beginning of the period	177,236	112,250	146,087
Cash, cash equivalents, and restricted cash at the end of the period	58,648	177,236	112,250
Non-cash financing and investing activities:
Acquisition of operating lease right-of-use assets		5,971
Acquisition of property and equipment in accounts payable and accrued liabilities	7		2,537
Remeasurement of operating lease right-of-use assets and lease liability		5,668
Reconciliation of cash, cash equivalents, and restricted cash:
Cash and cash equivalents	58,279	176,866	111,899
Restricted cash	369	370	351
Cash, cash equivalents, and restricted cash at the end of the period	$ 58,648	$ 177,236	$ 112,250