X0306 4/A 2021-04-15 2021-08-19 0 0001840439 Biomea Fusion, Inc. BMEA 0001455767 Erdtmann Rainer M C/O BIOMEA FUSION, INC. 900 MIDDLEFIELD ROAD, 4TH FLOOR REDWOOD CITY CA 94063 1 1 1 0 President and COO Common Stock 2021-04-15 4 P 0 2400 17.00 A 2400 I By daughter Common Stock 2021-04-15 4 P 0 3000 17.00 A 3000 I By daughter Common Stock 2021-04-15 4 P 0 3000 17.00 A 3000 I By son /s/ Franco Valle as Attorney-in-fact for Rainer M. Erdtmann 2023-02-10