X0306 4 2022-06-22 0 0001840439 Biomea Fusion, Inc. BMEA 0001262325 AGUIAR ERIC C/O BIOMEA FUSION, INC. 900 MIDDLEFIELD ROAD, 4TH FLOOR REDWOOD CITY CA 94063 1 0 0 0 Stock Option (Right to Buy) 10.20 2022-06-22 4 A 0 23867 0.00 A 2032-06-21 Common Stock 23867 23867 D The shares underlying the stock option will vest in full upon the earlier of (i) the one-year anniversary of the date of grant or (ii) immediately prior to the annual meeting of the Issuer's stockholders that occurs following the date of grant, subject to the Reporting Person's continued service to the Issuer through such vesting date. Exhibit 24 - Power of Attorney /s/ Franco Valle as Attorney-in-Fact for Eric Aguiar 2022-06-24