X0206 3 2021-04-15 0 0001840439 Biomea Fusion, Inc. BMEA 0001859061 A2A Pharmaceuticals, Inc. C/O BIOMEA FUSION, INC. 726 MAIN ST REDWOOD CITY CA 94063 0 0 1 0 Common Stock 4365342 D These shares are held directly by A2A Pharmaceuticals In. Sotirios Stergiopoulos is a members of the Issuer's Board of Directors and is an affiliate of the Reporting Person. /s/ Sotirios Stergiopoulos, CEO 2021-04-26