Income Taxes - Effective income tax rate reconciliation (Details)	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Effective income tax rate reconciliation
Tax effected at statutory rate	21.00%	21.00%
State taxes	7.40%	6.50%
Stock-based compensation	(1.00%)	(1.40%)
Non-deductible expenses	(1.20%)	(0.80%)
Federal research and development credits	4.00%	3.50%
Change in valuation allowance	(30.20%)	(28.80%)
Effective income tax rate	0.00%	0.00%