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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Cash flows from operating activities:    
Net loss $ (58,241) $ (76,404)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,644 1,900
Non-cash interest (income) expense   157
Stock-based compensation expense 6,434 7,382
Loss on disposal of property and equipment 3 3
Changes in operating assets and liabilities:    
Prepaid and other assets (1,520) 688
Operating lease right-of-use asset 539 460
Accounts payable 1,526 (2,063)
Accrued expenses and other liabilities (496) 175
Deferred revenue 32,780  
Operating lease liability (1,047) (918)
Net cash used in operating activities (18,378) (68,620)
Cash flows from investing activities:    
Purchases of property and equipment (36) (486)
Net cash used in investing activities (36) (486)
Cash flows from financing activities:    
Repayments of debt principal (3,333) (6,667)
Payments of finance lease (49) (85)
Proceeds from issuance of common stock under employee stock purchase plan 68 194
Proceeds from exercise of stock options 5 8
Proceeds from issuance of common stock in connection with at-the-market offering 6,825  
Net cash provided by (used in) financing activities 29,196 (6,550)
Increase (decrease) in cash, cash equivalents and restricted cash 10,782 (75,656)
Cash, cash equivalents and restricted cash, beginning of period 46,291 121,947
Cash, cash equivalents and restricted cash, end of period 57,073 46,291
Supplemental cash flow disclosure:    
Cash paid for interest 62 573
Supplemental disclosure of non-cash activities:    
Transfer of finance lease asset to property and equipment 85  
Reconciliation to amounts within the consolidated balance sheets:    
Cash and cash equivalents 55,291 44,704
Restricted cash 1,782 1,587
Cash, cash equivalents and restricted cash, end of period 57,073 $ 46,291
Gilead Stock Purchase Agreement    
Cash flows from financing activities:    
Proceeds from issuance of common stock and prefunded warrants in connection with the stock purchase agreement/private placement, net of issuance costs 15,772  
Private Placement    
Cash flows from financing activities:    
Proceeds from issuance of common stock and prefunded warrants in connection with the stock purchase agreement/private placement, net of issuance costs $ 9,908