Preferred Stock and Common Stock - Shares Reserved for Future Issuance (Details) - shares	Dec. 31, 2024	Dec. 31, 2023	Oct. 31, 2021
Shares for future issuance
Shares reserved for future issuance (in shares)	37,834,680	10,160,112
Prefunded warrants
Shares for future issuance
Shares reserved for future issuance (in shares)	25,602,707
Warrants, Excluding prefunded warrants
Shares for future issuance
Shares reserved for future issuance (in shares)	2,631	2,631
2021 ESPP
Shares for future issuance
Shares reserved for future issuance (in shares)	901,208	701,244	292,031
Stock options and unvested restricted stock units | 2020 Plan, 2021 Plan and 2022 Inducement Plan
Shares for future issuance
Shares reserved for future issuance (in shares)	11,328,134	9,456,237