CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands	Common Stock Gilead Stock Purchase Agreement	Common Stock Private Placement	Common Stock	Additional Paid-in Capital Gilead Stock Purchase Agreement	Additional Paid-in Capital Private Placement	Additional Paid-in Capital	Accumulated Deficit	Gilead Stock Purchase Agreement	Private Placement	Total
Beginning balance at Dec. 31, 2022			$ 3			$ 354,752	$ (249,108)			$ 105,647
Beginning balance (in shares) at Dec. 31, 2022			27,425,447
Stockholders' Deficit
Issuance of common stock under employee stock purchase plan						194				194
Issuance of common stock under employee stock purchase plan (in shares)			140,192
Vesting of restricted common stock (in shares)			39,250
Exercise of stock options						8				8
Exercise of stock options (in shares)			2,757
Stock-based compensation expense						7,382				7,382
Net Income (Loss)							(76,404)			(76,404)
Ending balance at Dec. 31, 2023			$ 3			362,336	(325,512)			36,827
Ending balance (in shares) at Dec. 31, 2023			27,607,646
Stockholders' Deficit
Issuance of common stock and prefunded warrants, net of issuance costs	$ 1			$ 15,771	$ 9,908			$ 15,772	$ 9,908
Issuance of common stock and prefunded warrants, net of issuance costs (in shares)	9,105,451	1,953,125
Issuance of common stock in connection with at-the-market offerings, net of issuance costs			$ 1			6,824				6,825
Issuance of common stock in connection with at-the-market offerings, net of issuance costs (in shares)			7,000,000
Issuance of common stock under employee stock purchase plan						68				68
Issuance of common stock under employee stock purchase plan (in shares)			76,168
Vesting of restricted common stock (in shares)			5,617
Exercise of stock options						5				$ 5
Exercise of stock options (in shares)			8,766							8,766
Stock-based compensation expense						6,434				$ 6,434
Net Income (Loss)							(58,241)			(58,241)
Ending balance at Dec. 31, 2024			$ 5			$ 401,346	$ (383,753)			$ 17,598
Ending balance (in shares) at Dec. 31, 2024			45,756,773