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Description of Business and Liquidity and Going Concern - Liquidity and Going Concern (Details) - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Feb. 28, 2025
Dec. 31, 2024
Dec. 31, 2023
Agreements      
Accumulated deficit   $ 383,753 $ 325,512
Net loss   58,241 76,404
Cash and cash equivalents   $ 55,291 $ 44,704
Substantial doubt about going concern within one year   true  
Collaboration, license and option agreement and Stock purchase agreement | AbbVie Group Holdings | Subsequent events      
Agreements      
Upfront payment from agreement and proceeds from private placement $ 52,000