Description of Business and Liquidity and Going Concern - Liquidity and Going Concern (Details) - USD ($) $ in Thousands				12 Months Ended
	Apr. 02, 2024	Mar. 28, 2024	Mar. 27, 2024	Dec. 31, 2023	Dec. 31, 2022
Agreements
Accumulated deficit				$ 325,512	$ 249,108
Net loss				76,404	88,222
Cash and cash equivalents				$ 44,704	$ 120,385
Substantial doubt about going concern within one year				true
Initial Gilead Private Placement | Subsequent events
Agreements
Aggregate gross proceeds from private placement (in dollars)		$ 13,500
March 2024 Private Placement | Forecast
Agreements
Aggregate gross proceeds from private placement (in dollars)	$ 11,300
License Agreement | Gilead Sciences, Inc. | Subsequent events
Agreements
Upfront cash payment to be received			$ 30,000