CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Current assets
Cash and cash equivalents	$ 176,959	$ 198,053
Prepaid expenses and other current assets	4,128	4,464
Total current assets	181,087	202,517
Restricted cash	1,553	1,553
Property and equipment, net	7,468	7,620
Operating lease right-of-use asset	5,885	5,977
Other non-current assets	359	393
Total assets	196,352	218,060
Current liabilities
Accounts payable	2,324	3,144
Accrued expenses	7,323	8,751
Operating lease liability, current portion	829	801
Notes payable, current portion	1,667
Other current liabilities	82	82
Total current liabilities	12,225	12,778
Notes payable, net of current portion	8,012	9,628
Operating lease liability, net of current portion	9,894	10,107
Other liabilities, long-term	100	118
Total liabilities	30,231	32,631
Commitments and contingencies (Note 7)
Stockholders' equity
Preferred stock, $0.0001 par value; 5,000,000 shares authorized, no shares issued or outstanding at March 31, 2022 and December 31, 2021
Common stock, $0.0001 par value; 200,000,000 shares authorized at March 31, 2022 and December 31, 2021; 27,471,607 shares issued and 27,376,473 shares outstanding at March 31, 2022; 27,468,950 shares issued and 27,358,375 shares outstanding at December 31, 2021	3	3
Additional paid-in capital	348,357	346,312
Accumulated deficit	(182,239)	(160,886)
Total stockholders' equity (deficit)	166,121	185,429
Total liabilities and stockholders' equity	$ 196,352	$ 218,060