TEXT-EXTRACT 2 filename2.txt United States securities and exchange commission logo August 12, 2021 Jennifer Buell, Ph.D. President, Chief Executive Officer and Director MiNK Therapeutics, Inc. 149 Fifth Avenue Suite 500 New York, NY 10010 Re: MiNK Therapeutics, Inc. Amendment No. 2 to Draft Registration Statement on Form S-1 Submitted July 28, 2021 CIK No. 0001840229 Dear Dr. Buell: We have reviewed your amended draft registration statement and have the following comment. Please respond to this letter by providing the requested information and either submitting an amended draft registration statement or publicly filing your registration statement on EDGAR. If you do not believe our comment applies to your facts and circumstances or do not believe an amendment is appropriate, please tell us why in your response. After reviewing the information you provide in response to this comment and your amended draft registration statement or filed registration statement, we may have additional comments. Amendment No.2 to Draft Registration Statement on Form S-1 Key Features of iNKT Cells Naturally Suited for Allogeneic Approaches, page 83 1. We note your disclosure that "[i]n both clinical and preclinical studies, iNKT cells have been observed not to cause, but instead to actively suppress, GvHD, lowering the safety risks associated with other allogeneic immune cells." With reference to your disclosure on page 14, please revise the disclosure on page 83 to provide context to these observations by explaining, if true, that no allogeneic iNKT cell therapy has been deemed safe or been approved by FDA or by any comparable regulatory authority. Jennifer Buell, Ph.D. FirstName LastNameJennifer Buell, Ph.D. MiNK Therapeutics, Inc. Comapany August 12, NameMiNK 2021 Therapeutics, Inc. August Page 2 12, 2021 Page 2 FirstName LastName You may contact Nudrat Salik at 202-551-3692 or Daniel Gordon at 202-551-3486 if you have questions regarding comments on the financial statements and related matters. Please contact Dillon Hagius at 202-551-7967 or Joe McCann at 202-551-6262 with any other questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Zachary Blume