X0306 4 2021-01-12 0 0001789972 Cullinan Management, Inc. CGEM 0001575745 Jovan-Embiricos Morana C/O CULLINAN MANAGEMENT, INC. ONE MAIN STREET, SUITE 520 CAMBRIDGE MA 02142 1 0 1 0 0001600769 Globeways Holdings Ltd C/O LJ PARTNERSHIP, 8, RUE SAINT-LEGER, GENEVA V8 CH-1205 SWITZERLAND 0 0 1 0 0001838409 F2 Vision SCS C/O ATALUX 74 GRAND-RUE LUXEMBOURG V8 L-1660 SWITZERLAND 0 0 1 0 0001838573 F2 Bioscience I 2017 Ltd C/O LJ PARTNERSHIP, 8, RUE SAINT-LEGER, GENEVA V8 CH-1205 SWITZERLAND 0 0 1 0 0001767396 F2 MG Ltd C/O LJ PARTNERSHIP, 8, RUE SAINT-LEGER GENEVA V8 CH-1205 SWITZERLAND 0 0 1 0 0001767397 F2 - TPO Investments LLC C/O SINGER, MCKEON INC. 8 WEST 38TH STREET, SUITE 1001 NEW YORK NY 10018 0 0 1 0 0001838330 F2 Bio TD, LLC C/O SINGER, MCKEON INC. 8 WEST 38TH STREET, SUITE 1001 NEW YORK NY 10018 0 0 1 0 0001838426 F2 MC, LLC C/O SINGER, MCKEON INC. 8 WEST 38TH STREET, SUITE 1001 NEW YORK NY 10018 0 0 1 0 0001840637 F2 GC, LLC C/O SINGER, MCKEON INC. 8 WEST 38TH STREET, SUITE 1001 NEW YORK NY 10018 0 0 1 0 Common Stock 112507 D Common Stock 2021-01-12 4 C 0 1136525 A 1136525 I See Footnote Common Stock 2021-01-12 4 C 0 2912345 A 2912345 I See Footnote Common Stock 2021-01-12 4 C 0 639295 A 639295 I See Footnote Common Stock 2021-01-12 4 C 0 455338 A 455338 I See Footnote Common Stock 2021-01-12 4 C 0 182135 A 182135 I See Footnote Common Stock 2021-01-12 4 C 0 71599 A 526937 I See Footnote Common Stock 2021-01-12 4 C 0 143198 A 325333 I See Footnote Common Stock 2021-01-12 4 C 0 71599 A 71599 I See Footnote Common Stock 2021-01-12 4 C 0 214798 A 214798 I See Footnote Common Stock 2021-01-12 4 P 0 95238 21.00 A 622175 I See Footnote Common Stock 2021-01-12 4 P 0 104762 21.00 A 104762 I See Footnote Series Seed Convertible Preferred Stock 2021-01-12 4 C 0 8000000 0.00 D Common Stock 1136525 0 I See Footnote Series A Convertible Preferred Stock 2021-01-12 4 C 0 20500000 0.00 D Common Stock 2912345 0 I See Footnote Series A Convertible Preferred Stock 2021-01-12 4 C 0 4500000 0.00 D Common Stock 639295 0 I See Footnote Series B Convertible Preferred Stock 2021-01-12 4 C 0 3205128 0.00 D Common Stock 455338 0 I See Footnote Series B Convertible Preferred Stock 2021-01-12 4 C 0 1282051 0.00 D Common Stock 182135 0 I See Footnote Series C Convertible Preferred Stock 2021-01-12 4 C 0 503988 0.00 D Common Stock 71599 0 I See Footnote Series C Convertible Preferred Stock 2021-01-12 4 C 0 1007977 0.00 D Common Stock 143198 0 I See Footnote Series C Convertible Preferred Stock 2021-01-12 4 C 0 503988 0.00 D Common Stock 71599 0 I See Footnote Series C Convertible Preferred Stock 2021-01-12 4 C 0 1511966 0.00 D Common Stock 214798 0 I See Footnote Each share of Series Seed Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock (the "Preferred Stock') converted into Common Stock of the Issuer on a 1-for-7.0390 basis at the closing of the Issuer's initial public offering on January 12, 2021. The Preferred Stock had no expiration date. These securities are owned directly by Globeways Holdings Limited ("Globeways"). The Reporting Person is the founding director of Globeways and has the sole power to vote upon the acquisition, holding and disposal of all shares held by Globeways. The Reporting Person disclaims beneficial ownership of these securities except to the extent of her pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose. These securities are owned directly by F2 Vision SCS ("F2 Vision"). F2 Vision Management Sarl ("F2 Vision Management") is the appointed manager of F2 Vision. The Reporting Person is the founding director of F2 Vision Management and has the sole power to vote upon the acquisition, holding and disposal of all shares held by F2 Vision. The Reporting Person disclaims beneficial ownership of these securities except to the extent of her pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose. These securities are owned directly by F2 Bioscience I 2017 Limited ("F2 Bioscience 2017"). Globeways is the appointed manager of F2 Bioscience 2017. The Reporting Person is the founding director of Globeways and has the sole power to vote upon the acquisition, holding and disposal of all shares held by F2 Bioscience 2017. The Reporting Person disclaims beneficial ownership of these securities except to the extent of her pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose. These securities are owned directly by F2-TPO Investments, LLC ("F2-TPO"). Globeways Holdings II Limited ("Globeways II") is the appointed manager of F2-TPO. The Reporting Person is the founding director of Globeways II and has the sole power to vote upon the acquisition, holding and disposal of all shares held by F2-TPO. The Reporting Person disclaims beneficial ownership of these securities except to the extent of her pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose. These securities are owned directly by F2 MG Limited ("F2 MG"). Globeways is the appointed manager of F2 MG. The Reporting Person is the founding director of Globeways and has the sole power to vote upon the acquisition, holding and disposal of all shares held by F2 MG. The Reporting Person disclaims beneficial ownership of these securities except to the extent of her pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose. These securities are owned directly by F2 Bio TD, LLC ("F2 Bio"). Globeways II is the appointed manager of F2 Bio. The Reporting Person is the founding director of Globeways II and has the sole power to vote upon the acquisition, holding and disposal of all shares held by F2 Bio. . The Reporting Person disclaims beneficial ownership of these securities except to the extent of her pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose. These securities are owned directly by F2 MC, LLC ("F2 MC"). Globeways II is the appointed manager of F2 MC. The Reporting Person is the founding director of Globeways II and has the sole power to vote upon the acquisition, holding and disposal of all shares held by F2 MC. The Reporting Person disclaims beneficial ownership of these securities except to the extent of her pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose. These securities are owned directly by F2 GC LLC ("F2 GC"). Globeways II is the appointed manager of F2 GC. The Reporting Person is the founding director of Globeways II and has the sole power to vote upon the acquisition, holding and disposal of all shares held by F2 GC. The Reporting Person disclaims beneficial ownership of these securities except to the extent of her pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose. /s/ Morana Jovan-Embiricos 2021-01-14 /s/ Morana Jovan-Embiricos for Globeways Holdings Limited 2021-01-14 /s/ Alain Renard and Christian Francois for F2 Vision SCS 2021-01-14 /s/ Rachel Higham and Ivan Bedford for F2 Bioscience I 2017 Limited 2021-01-14 /s/ Morana Jovan-Embiricos for F2-TPO Investments, LLC 2021-01-14 /s/ Rachel Higham and Ivan Bedford for F2 MG Limited 2021-01-14 /s/ Morana Jovan-Embiricos for F2 Bio TD, LLC 2021-01-14 /s/ Morana Jovan-Embiricos for F2 MC, LLC 2021-01-14 /s/ Morana Jovan-Embiricos for F2 GC, LLC 2021-01-14