The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COM 002824100   35,772,750 325,000 SH   DFND 1 325,000 0 0
ABBVIE INC COM 00287Y109   56,069,386 361,808 SH   DFND 1 361,808 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109   84,955,677 1,092,537 SH   DFND 1 1,092,537 0 0
ADDUS HOMECARE CORP COM 006739106   31,214,313 336,180 SH   DFND 1 336,180 0 0
ADOBE INC COM 00724F101   114,312,736 191,607 SH   DFND 1 191,607 0 0
ADVANCED MICRO DEVICES INC COM 007903107   497,368,416 3,374,048 SH   DFND 1 3,374,048 0 0
AFFILIATED MANAGERS GROUP IN COM 008252108   10,142,263 66,981 SH   DFND 1 66,981 0 0
AFLAC INC COM 001055102   40,012,500 485,000 SH   DFND 1 485,000 0 0
AIR PRODS & CHEMS INC COM 009158106   8,788,980 32,100 SH   DFND 1,2 32,100 0 0
AKAMAI TECHNOLOGIES INC NOTE 0.125% 5/0 00971TAJ0   12,730,800 10,000,000 PRN   DFND 1 10,000,000 0 0
AKOYA BIOSCIENCES INC COM 00974H104   7,709,209 1,579,756 SH   DFND 1 1,579,756 0 0
ALBEMARLE CORP COM 012653101   5,605,824 38,800 SH   DFND 1,2 38,800 0 0
ALCON AG ORD SHS H01301128   23,407,974 340,473 SH   DFND 1 340,473 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   35,410,850 185,000 SH   DFND 1 185,000 0 0
ALNYLAM PHARMACEUTICALS INC NOTE 1.000% 9/1 02043QAB3   3,950,480 4,000,000 PRN   DFND 1 4,000,000 0 0
ALPHABET INC CAP STK CL C 02079K107   347,510,408 2,465,837 SH   DFND 1 2,465,837 0 0
ALPHABET INC CAP STK CL A 02079K305   338,077,598 2,420,199 SH   DFND 1 2,420,199 0 0
AMAZON COM INC COM 023135106   313,349,205 2,062,322 SH   DFND 1 2,062,322 0 0
AMDOCS LTD SHS G02602103   21,759,367 247,575 SH   DFND 1 247,575 0 0
AMERICAN EXPRESS CO COM 025816109   10,089,945 53,859 SH   DFND 1 53,859 0 0
AMGEN INC COM 031162100   70,562,596 244,992 SH   DFND 1 244,992 0 0
ANALOG DEVICES INC COM 032654105   30,663,621 154,430 SH   DFND 1,2 154,430 0 0
ANSYS INC COM 03662Q105   9,453,024 26,050 SH   DFND 1,2 26,050 0 0
AON PLC SHS CL A G0403H108   59,659,100 205,000 SH   DFND 1 205,000 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   63,058,918 1,053,440 SH   DFND 1 1,053,440 0 0
APPLE INC COM 037833100   553,351,553 2,880,033 SH   DFND 1 2,880,033 0 0
APTARGROUP INC COM 038336103   18,160,767 146,908 SH   DFND 1 146,908 0 0
APTIV PLC SHS G6095L109   358,880 4,000 SH   DFND 2 4,000 0 0
ARCH CAP GROUP LTD ORD G0450A105   233,444,870 3,143,192 SH   DFND 1 3,143,192 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108   20,341,532 6,297,688 SH   DFND 1 6,297,688 0 0
ARES CAPITAL CORP COM 04010L103   3,925,319 195,972 SH   DFND 1 195,972 0 0
ARES MANAGEMENT CORPORATION CL A COM STK 03990B101   8,180,507 68,790 SH   DFND 1 68,790 0 0
ARISTA NETWORKS INC COM 040413106   185,726,012 788,612 SH   DFND 1 788,612 0 0
ARM HOLDINGS PLC SPONSORED ADR 042068205   71,308,597 1,005,763 SH Call DFND 1 1,005,763 0 0
ARRAY TECHNOLOGIES INC NOTE 1.000%12/0 04271TAB6   14,139,773 14,350,000 PRN   DFND 1 14,350,000 0 0
ASCENDIS PHARMA A/S NOTE 2.250% 4/0 04351PAD3   12,361,800 12,000,000 PRN   DFND 1 12,000,000 0 0
ATLASSIAN CORPORATION CL A 049468101   10,339,774 43,470 SH   DFND 1 43,470 0 0
AUTODESK INC COM 052769106   12,880,092 52,900 SH   DFND 1,2 52,900 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104   95,335,162 6,751,782 SH   DFND 1 6,751,782 0 0
AXON ENTERPRISE INC COM 05464C101   57,245,411 221,598 SH   DFND 1 221,598 0 0
BAIDU INC SPON ADR REP A 056752108   16,452,641 138,153 SH   DFND 1 138,153 0 0
BAKER HUGHES COMPANY CL A 05722G100   8,359,847 244,583 SH   DFND 1 244,583 0 0
BANK AMERICA CORP COM 060505104   16,372,475 486,263 SH   DFND 1 486,263 0 0
BECTON DICKINSON & CO COM 075887109   14,996,520 61,504 SH   DFND 1 61,504 0 0
BERKLEY W R CORP COM 084423102   134,898,400 1,907,500 SH   DFND 1 1,907,500 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702   55,205,975 154,786 SH   DFND 1 154,786 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108   18,161,993 1,004,535 SH   DFND 1 1,004,535 0 0
BIO RAD LABS INC CL A 090572207   17,024,698 52,726 SH   DFND 1 52,726 0 0
BIOCERES CROP SOLUTIONS CORP SHS G1117K114   16,421,808 1,196,053 SH   DFND 1 1,196,053 0 0
BIOGEN INC COM 09062X103   77,631,000 300,000 SH   DFND 1 300,000 0 0
BLACKLINE INC NOTE 3/1 09239BAD1   12,328,034 13,950,000 PRN   DFND 1 13,950,000 0 0
BLACKROCK INC COM 09247X101   8,816,960 10,861 SH   DFND 1 10,861 0 0
BLOCK INC CL A 852234103   17,488,526 226,096 SH   DFND 1 226,096 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109   79,787,600 865,000 SH   DFND 1 865,000 0 0
BOOKING HOLDINGS INC COM 09857L108   18,764,794 5,290 SH   DFND 1 5,290 0 0
BORGWARNER INC COM 099724106   286,800 8,000 SH   DFND 2 8,000 0 0
BOSTON SCIENTIFIC CORP COM 101137107   58,567,600 1,013,105 SH   DFND 1 1,013,105 0 0
BRAZE INC COM CL A 10576N102   11,123,350 209,361 SH   DFND 1 209,361 0 0
BROADCOM INC COM 11135F101   80,470,463 72,090 SH   DFND 1 72,090 0 0
BRUKER CORP COM 116794108   203,613 2,771 SH   DFND 1 2,771 0 0
CABALETTA BIO INC COM 12674W109   28,375,000 1,250,000 SH   DFND 1 1,250,000 0 0
CADENCE DESIGN SYSTEM INC COM 127387108   95,924,628 352,185 SH   DFND 1 352,185 0 0
CANADIAN NAT RES LTD COM 136385101   10,898,932 141,386 SH   DFND 1 141,386 0 0
CANNAE HLDGS INC COM 13765N107   9,289,413 476,136 SH   DFND 1 476,136 0 0
CARRIER GLOBAL CORPORATION COM 14448C104   3,274,650 57,000 SH   DFND 1,2 57,000 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202   124,368,644 3,135,871 SH   DFND 1 3,135,871 0 0
CENOVUS ENERGY INC COM 15135U109   18,187,533 923,339 SH   DFND 1 923,339 0 0
CENTENE CORP DEL COM 15135B101   21,554,517 290,453 SH   DFND 1 290,453 0 0
CERIDIAN HCM HLDG INC NOTE 0.250% 3/1 15677JAD0   10,158,748 11,288,000 PRN   DFND 1 11,288,000 0 0
CERUS CORP COM 157085101   57,326 26,540 SH   DFND 1 26,540 0 0
CHEMED CORP NEW COM 16359R103   4,797,874 8,205 SH   DFND 1 8,205 0 0
CHEWY INC CL A 16679L109   6,265,636 265,156 SH   DFND 1 265,156 0 0
CHUBB LIMITED COM H1467J104   204,245,466 903,741 SH   DFND 1 903,741 0 0
CLOUDFLARE INC CL A COM 18915M107   60,798,367 730,223 SH   DFND 1 730,223 0 0
COCA-COLA EUROPACIFIC PARTNE SHS G25839104   10,337,893 154,898 SH   DFND 1 154,898 0 0
COGNEX CORP COM 192422103   22,016,765 527,474 SH   DFND 1,2 527,474 0 0
COHERENT CORP COM 19247G107   6,812,010 156,490 SH   DFND 1 156,490 0 0
CORE & MAIN INC CL A 21874C102   13,358,980 330,586 SH   DFND 1 330,586 0 0
CRH PLC ORD G25508105   41,786,265 604,197 SH   DFND 1 604,197 0 0
CROWDSTRIKE HLDGS INC CL A 22788C105   191,848,469 751,404 SH   DFND 1 751,404 0 0
CYBERARK SOFTWARE LTD SHS M2682V108   107,270,756 489,709 SH   DFND 1 489,709 0 0
CYTOKINETICS INC NOTE 3.500% 7/0 23282WAC4   3,002,064 1,700,000 PRN   DFND 1 1,700,000 0 0
CYTOKINETICS INC COM NEW 23282W605   118,309,838 1,417,054 SH   DFND 1 1,417,054 0 0
DATADOG INC NOTE 0.125% 6/1 23804LAB9   12,222,438 8,750,000 PRN   DFND 1 8,750,000 0 0
DATADOG INC CL A COM 23804L103   77,982,159 642,463 SH   DFND 1 642,463 0 0
DAY ONE BIOPHARMACEUTICALS I COM 23954D109   20,221,000 1,385,000 SH   DFND 1 1,385,000 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101   29,840,500 1,850,000 SH   DFND 1 1,850,000 0 0
DEERE & CO COM 244199105   4,008,297 10,024 SH   DFND 1 10,024 0 0
DENALI THERAPEUTICS INC COM 24823R105   9,714,277 452,669 SH   DFND 1 452,669 0 0
DEXCOM INC COM 252131107   30,360,728 244,667 SH   DFND 1 244,667 0 0
DISC MEDICINE INC COM 254604101   31,589,810 546,915 SH   DFND 1 546,915 0 0
DOORDASH INC CL A 25809K105   68,210,960 689,766 SH   DFND 1 689,766 0 0
DOUBLEVERIFY HLDGS INC COM 25862V105   11,762,832 319,816 SH   DFND 1 319,816 0 0
DROPBOX INC NOTE 3/0 26210CAD6   4,024,800 4,000,000 PRN   DFND 1 4,000,000 0 0
DYNATRACE INC COM NEW 268150109   21,807,255 398,743 SH   DFND 1 398,743 0 0
EAST WEST BANCORP INC COM 27579R104   8,495,352 118,073 SH   DFND 1 118,073 0 0
EATON CORP PLC SHS G29183103   3,087,553 12,821 SH   DFND 1 12,821 0 0
ELASTIC N V ORD SHS N14506104   97,622,994 866,220 SH   DFND 1 866,220 0 0
ELEVANCE HEALTH INC COM 036752103   56,113,754 118,996 SH   DFND 1 118,996 0 0
ELI LILLY & CO COM 532457108   64,436,560 110,541 SH   DFND 1 110,541 0 0
EMERSON ELEC CO COM 291011104   2,680,566 27,541 SH   DFND 1 27,541 0 0
ENERSYS COM 29275Y102   6,935,952 68,700 SH   DFND 1,2 68,700 0 0
ENPHASE ENERGY INC COM 29355A107   13,874,700 105,000 SH   DFND 1 105,000 0 0
ENVISTA HOLDINGS CORPORATION COM 29415F104   12,112,742 503,439 SH   DFND 1 503,439 0 0
ESSENT GROUP LTD COM G3198U102   125,916,750 2,387,500 SH   DFND 1 2,387,500 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   5,864,577 226,519 SH   DFND 1 226,519 0 0
EVEREST GROUP LTD COM G3223R108   102,884,001 290,978 SH   DFND 1 290,978 0 0
EXACT SCIENCES CORP NOTE 0.375% 3/1 30063PAB1   9,721,600 10,000,000 PRN   DFND 1 10,000,000 0 0
EXELIXIS INC COM 30161Q104   7,259,518 302,606 SH   DFND 1 302,606 0 0
FABRINET SHS G3323L100   108,155,784 568,254 SH   DFND 1 568,254 0 0
FERGUSON PLC NEW SHS G3421J106   1,847,267,493 184,295 SH   DFND 1 184,295 0 0
FIDELITY NATL INFORMATION SV COM 31620M106   11,642,047 193,808 SH   DFND 1 193,808 0 0
FIRST AMERN FINL CORP COM 31847R102   45,108,000 700,000 SH   DFND 1 700,000 0 0
FISERV INC COM 337738108   17,651,248 132,876 SH   DFND 1 132,876 0 0
GLOBANT S A COM L44385109   40,101,534 168,508 SH   DFND 1 168,508 0 0
GOLUB CAP BDC INC COM 38173M102   3,169,188 209,880 SH   DFND 1 209,880 0 0
H WORLD GROUP LTD SPONSORED ADS 44332N106   3,155,465 94,362 SH   DFND 1 94,362 0 0
HAGERTY INC CL A COM 405166109   38,415,000 4,925,000 SH   DFND 1 4,925,000 0 0
HCA HEALTHCARE INC COM 40412C101   99,146,294 366,286 SH   DFND 1 366,286 0 0
HOLOGIC INC COM 436440101   5,402,978 75,619 SH   DFND 1 75,619 0 0
HUBSPOT INC COM 443573100   123,825,118 213,293 SH   DFND 1 213,293 0 0
HUMANA INC COM 444859102   12,926,265 28,235 SH   DFND 1 28,235 0 0
HYATT HOTELS CORP COM CL A 448579102   12,674,939 97,193 SH   DFND 1 97,193 0 0
ICON PLC SHS G4705A100   14,299,564 50,516 SH   DFND 1 50,516 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105   34,248,816 501,300 SH   DFND 1 501,300 0 0
IMPERIAL OIL LTD COM NEW 453038408   13,538,719 201,063 SH   DFND 1 201,063 0 0
IMPINJ INC NOTE 1.125% 5/1 453204AD1   3,578,447 3,280,000 PRN   DFND 1 3,280,000 0 0
INCYTE CORP COM 45337C102   5,651,100 90,000 SH   DFND 1 90,000 0 0
INSMED INC COM PAR $.01 457669307   15,627,482 504,275 SH   DFND 1 504,275 0 0
INSULET CORP COM 45784P101   24,078,488 110,971 SH   DFND 1 110,971 0 0
INSULET CORP NOTE 0.375% 9/0 45784PAK7   3,446,760 3,000,000 PRN   DFND 1 3,000,000 0 0
INTERACTIVE BROKERS GROUP IN COM CL A 45841N107   19,670,844 237,284 SH   DFND 1 237,284 0 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104   32,916,866 256,302 SH   DFND 1 256,302 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   66,516,717 928,745 SH   DFND 1 928,745 0 0
INTUIT COM 461202103   24,713,686 39,540 SH   DFND 1 39,540 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602   107,537,886 318,763 SH   DFND 1 318,763 0 0
IQVIA HLDGS INC COM 46266C105   19,659,664 84,967 SH   DFND 1 84,967 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106   336,855 3,147 SH   DFND 1 3,147 0 0
JAMES RIV GROUP LTD COM G5005R107   11,665,500 1,262,500 SH   DFND 1 1,262,500 0 0
JAZZ INVESTMENTS I LTD NOTE 2.000% 6/1 472145AF8   4,037,200 4,000,000 PRN   DFND 1 4,000,000 0 0
JFROG LTD ORD SHS M6191J100   19,413,303 560,916 SH   DFND 1 560,916 0 0
JOHNSON & JOHNSON COM 478160104   7,951,420 50,730 SH   DFND 1 50,730 0 0
JPMORGAN CHASE & CO COM 46625H100   44,204,737 259,875 SH   DFND 1 259,875 0 0
KE HLDGS INC SPONSORED ADS 482497104   166,039 10,243 SH   DFND 1 10,243 0 0
KLA CORP COM NEW 482480100   137,147,853 235,933 SH   DFND 1 235,933 0 0
KLAVIYO INC COM SER A 49845K101   6,794,516 244,583 SH   DFND 1 244,583 0 0
LANTHEUS HLDGS INC NOTE 2.625%12/1 516544AB9   2,793,950 2,500,000 PRN   DFND 1 2,500,000 0 0
LATTICE SEMICONDUCTOR CORP COM 518415104   75,833,532 1,099,196 SH   DFND 1,2 1,099,196 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102   82,461,541 1,370,476 SH   DFND 1 1,370,476 0 0
LENNOX INTL INC COM 526107107   11,568,392 25,850 SH   DFND 1,2 25,850 0 0
LIBERTY MEDIA CORP DEL NOTE 2.250% 8/1 531229AQ5   1,827,864 1,800,000 PRN   DFND 1 1,800,000 0 0
LIBERTY MEDIA CORP DEL COM LBTY ONE S C 531229755   12,656,050 200,476 SH   DFND 1 200,476 0 0
LIFESTANCE HEALTH GROUP INC COM 53228F101   110,677 14,135 SH   DFND 1 14,135 0 0
LINDE PLC SHS G54950103   35,451,255 86,317 SH   DFND 1,2 86,317 0 0
LITTELFUSE INC COM 537008104   12,698,933 47,462 SH   DFND 1 47,462 0 0
LIVANOVA PLC SHS G5509L101   8,983,668 173,631 SH   DFND 1 173,631 0 0
LIVENT CORP COM 53814L108   6,023,300 335,000 SH   DFND 1,2 335,000 0 0
LONGBOARD PHARMACEUTICALS IN COM 54300N103   6,030,000 1,000,000 SH   DFND 1 1,000,000 0 0
MAKEMYTRIP LIMITED MAURITIUS SHS V5633W109   43,007,935 915,452 SH   DFND 1 915,452 0 0
MARKEL GROUP INC COM 570535104   120,691,500 85,000 SH   DFND 1 85,000 0 0
MARRIOTT INTL INC NEW CL A 571903202   8,359,430 37,069 SH   DFND 1 37,069 0 0
MARSH & MCLENNAN COS INC COM 571748102   180,930,208 954,928 SH   DFND 1 954,928 0 0
MARVELL TECHNOLOGY INC COM 573874104   25,462,882 422,200 SH   DFND 1,2 422,200 0 0
MASTERCARD INCORPORATED CL A 57636Q104   66,624,701 156,209 SH   DFND 1 156,209 0 0
MCKESSON CORP COM 58155Q103   74,396,719 160,691 SH   DFND 1 160,691 0 0
MERCADOLIBRE INC COM 58733R102   49,571,086 31,543 SH   DFND 1 31,543 0 0
MERIT MED SYS INC COM 589889104   36,334,858 478,342 SH   DFND 1 478,342 0 0
META PLATFORMS INC CL A 30303M102   326,817,639 923,318 SH   DFND 1 923,318 0 0
MICRON TECHNOLOGY INC COM 595112103   165,983,398 1,944,966 SH   DFND 1 1,944,966 0 0
MICROSOFT CORP COM 594918104   743,214,481 1,976,424 SH   DFND 1 1,976,424 0 0
MIRUM PHARMACEUTICALS INC COM 604749101   18,450,000 625,000 SH   DFND 1 625,000 0 0
MKS INSTRS INC COM 55306N104   15,369,498 149,407 SH   DFND 1 149,407 0 0
MONDAY COM LTD SHS M7S64H106   58,547,138 311,736 SH   DFND 1 311,736 0 0
MONGODB INC CL A 60937P106   142,475,639 348,479 SH   DFND 1 348,479 0 0
MONOLITHIC PWR SYS INC COM 609839105   138,909,741 220,219 SH   DFND 1,2 220,219 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104   56,592,375 937,115 SH   DFND 1 937,115 0 0
MORGAN STANLEY COM NEW 617446448   11,114,374 119,189 SH   DFND 1 119,189 0 0
MP MATERIALS CORP COM CL A 553368101   11,860,375 597,500 SH   DFND 1,2 597,500 0 0
MSCI INC COM 55354G100   5,297,878 9,366 SH   DFND 1 9,366 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109   2,974,890 3,975,000 SH   DFND 1 3,975,000 0 0
NATERA INC COM 632307104   350,784 5,600 SH   DFND 1 5,600 0 0
NETFLIX INC COM 64110L106   127,038,677 260,924 SH   DFND 1 260,924 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109   110,129,356 835,833 SH   DFND 1 835,833 0 0
NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES N62509109   10,161,818 909,742 SH Call DFND 1 909,742 0 0
NIO INC SPON ADS 62914V106   4,988,500 550,000 SH   DFND 1,2 550,000 0 0
NORFOLK SOUTHN CORP COM 655844108   10,425,540 44,105 SH   DFND 1 44,105 0 0
NU HLDGS LTD ORD SHS CL A G6683N103   190,449 22,863 SH   DFND 1 22,863 0 0
NUTANIX INC NOTE 0.250%10/0 67059NAH1   25,387,703 24,510,000 PRN   DFND 1 24,510,000 0 0
NVIDIA CORPORATION COM 67066G104   722,038,684 1,458,016 SH   DFND 1 1,458,016 0 0
NXP SEMICONDUCTORS N V COM N6596X109   11,024,640 48,000 SH   DFND 1,2 48,000 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106   10,522,500 750,000 SH   DFND 1 750,000 0 0
ON SEMICONDUCTOR CORP COM 682189105   22,394,393 268,100 SH   DFND 1,2 268,100 0 0
PALO ALTO NETWORKS INC COM 697435105   114,034,224 386,714 SH   DFND 1 386,714 0 0
PATRICK INDS INC NOTE 1.750%12/0 703343AG8   3,448,500 3,000,000 PRN   DFND 1 3,000,000 0 0
PAYPAL HLDGS INC COM 70450Y103   206,583 3,364 SH   DFND 1 3,364 0 0
PDD HOLDINGS INC SPONSORED ADS 722304102   57,262,515 391,378 SH   DFND 1 391,378 0 0
PENUMBRA INC COM 70975L107   32,089,964 127,574 SH   DFND 1 127,574 0 0
PINTEREST INC CL A 72352L106   85,090,844 2,297,269 SH   DFND 1 2,297,269 0 0
PLIANT THERAPEUTICS INC COM 729139105   36,491,650 2,015,000 SH   DFND 1 2,015,000 0 0
POWER INTEGRATIONS INC COM 739276103   1,190,595 14,500 SH   DFND 1,2 14,500 0 0
PRIVIA HEALTH GROUP INC COM 74276R102   226,569 9,838 SH   DFND 1 9,838 0 0
PROASSURANCE CORP COM 74267C106   29,820,875 2,162,500 SH   DFND 1 2,162,500 0 0
PROGRESSIVE CORP COM 743315103   93,577,000 587,500 SH   DFND 1 587,500 0 0
PURE STORAGE INC CL A 74624M102   106,634,669 2,990,316 SH   DFND 1 2,990,316 0 0
QIAGEN NV SHS NEW N72482123   21,909,806 440,325 SH   DFND 1 440,325 0 0
QORVO INC COM 74736K101   9,459,240 84,000 SH   DFND 1,2 84,000 0 0
QUALCOMM INC COM 747525103   103,860,828 718,114 SH   DFND 1 718,114 0 0
R1 RCM INC COM 77634L105   127,125 12,027 SH   DFND 1 12,027 0 0
RAMBUS INC DEL COM 750917106   103,161,308 1,511,521 SH   DFND 1 1,511,521 0 0
REGENERON PHARMACEUTICALS COM 75886F107   173,767,042 197,847 SH   DFND 1 197,847 0 0
REINSURANCE GRP OF AMERICA I COM NEW 759351604   78,867,750 487,500 SH   DFND 1 487,500 0 0
RENAISSANCERE HLDGS LTD COM G7496G103   214,701,732 1,095,417 SH   DFND 1 1,095,417 0 0
REVANCE THERAPEUTICS INC COM 761330109   27,857,611 3,169,239 SH   DFND 1 3,169,239 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105   80,447,500 1,750,000 SH   DFND 1 1,750,000 0 0
RLI CORP COM 749607107   34,611,200 260,000 SH   DFND 1 260,000 0 0
ROBLOX CORP CL A 771049103   20,330,815 444,681 SH   DFND 1 444,681 0 0
ROCKWELL AUTOMATION INC COM 773903109   9,789,745 31,531 SH   DFND 1 31,531 0 0
ROYAL BK CDA COM 780087102   13,129,949 109,836 SH   DFND 1 109,836 0 0
RYAN SPECIALTY HOLDINGS INC CL A 78351F107   55,388,250 1,287,500 SH   DFND 1 1,287,500 0 0
S&P GLOBAL INC COM 78409V104   16,282,500 36,962 SH   DFND 1 36,962 0 0
SABRE CORP COM 78573M104   4,011,590 911,725 SH   DFND 1 911,725 0 0
SALESFORCE INC COM 79466L302   72,209,037 274,413 SH   DFND 1 274,413 0 0
SAREPTA THERAPEUTICS INC NOTE 1.250% 9/1 803607AD2   3,554,040 3,500,000 PRN   DFND 1 3,500,000 0 0
SCHLUMBERGER LTD COM STK 806857108   7,944,843 152,668 SH   DFND 1 152,668 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   55,284,634 2,940,672 SH   DFND 1 2,940,672 0 0
SEA LTD SPONSORD ADS 81141R100   17,508,150 432,300 SH   DFND 1 432,300 0 0
SERVICENOW INC COM 81762P102   170,348,162 241,119 SH   DFND 1 241,119 0 0
SHOCKWAVE MED INC COM 82489T104   24,183,588 126,908 SH   DFND 1 126,908 0 0
SHOPIFY INC CL A 82509L107   156,089,944 2,003,722 SH   DFND 1 2,003,722 0 0
SNOWFLAKE INC CL A 833445109   110,389,280 554,720 SH   DFND 1 554,720 0 0
SPOTIFY TECHNOLOGY S A SHS L8681T102   22,646,725 120,519 SH   DFND 1 120,519 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202   10,760,000 500,000 SH   DFND 1 500,000 0 0
SS&C TECHNOLOGIES HLDGS INC COM 78467J100   14,869,896 243,330 SH   DFND 1 243,330 0 0
SSR MINING IN NOTE 2.500% 4/0 784730AB9   2,412,629 2,549,000 PRN   DFND 1 2,549,000 0 0
STANDARD BIOTOOLS INC COM 34385P108   125,053 56,585 SH   DFND 1 56,585 0 0
STEREOTAXIS INC COM NEW 85916J409   122,022 69,727 SH   DFND 1 69,727 0 0
STRYKER CORPORATION COM 863667101   8,725,965 29,139 SH   DFND 1 29,139 0 0
SUPERNUS PHARMACEUTICALS INC COM 868459108   56,125,223 1,939,365 SH   DFND 1 1,939,365 0 0
SYNOPSYS INC COM 871607107   135,720,493 263,581 SH   DFND 1 263,581 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106   4,458,469 2,518,909 SH   DFND 1 2,518,909 0 0
TECK RESOURCES LTD CL B 878742204   12,237,545 289,509 SH   DFND 1 289,509 0 0
TENET HEALTHCARE CORP COM NEW 88033G407   20,918,003 276,803 SH   DFND 1 276,803 0 0
TESLA INC COM 88160R101   130,204,762 524,005 SH   DFND 1 524,005 0 0
THE TRADE DESK INC COM CL A 88339J105   69,975,919 972,428 SH   DFND 1 972,428 0 0
T-MOBILE US INC COM 872590104   13,920,011 86,821 SH   DFND 1 86,821 0 0
TORONTO DOMINION BK ONT COM NEW 891160509   7,269,848 95,178 SH   DFND 1 95,178 0 0
TRAVELERS COMPANIES INC COM 89417E109   104,105,261 546,513 SH   DFND 1 546,513 0 0
TRIMBLE INC COM 896239100   351,120 6,600 SH   DFND 2 6,600 0 0
TRUPANION INC COM 898202106   38,137,500 1,250,000 SH   DFND 1 1,250,000 0 0
UBER TECHNOLOGIES INC COM 90353T100   79,328,081 1,288,421 SH   DFND 1,2 1,288,421 0 0
UNION PAC CORP COM 907818108   19,781,744 80,538 SH   DFND 1 80,538 0 0
UNITED RENTALS INC COM 911363109   23,373,173 40,761 SH   DFND 1 40,761 0 0
US BANCORP DEL COM NEW 902973304   11,062,498 255,603 SH   DFND 1 255,603 0 0
US FOODS HLDG CORP COM 912008109   23,681,451 521,503 SH   DFND 1 521,503 0 0
VERA THERAPEUTICS INC CL A 92337R101   11,150,500 725,000 SH   DFND 1 725,000 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100   71,205,750 175,000 SH   DFND 1 175,000 0 0
VERTIV HOLDINGS CO COM CL A 92537N108   13,928,700 290,000 SH   DFND 1,2 290,000 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   21,342,592 979,917 SH   DFND 1 979,917 0 0
VIRTU FINL INC CL A 928254101   3,241,600 160,000 SH   DFND 1 160,000 0 0
VISA INC COM CL A 92826C839   64,767,009 248,769 SH   DFND 1 248,769 0 0
VISTEON CORP COM NEW 92839U206   287,270 2,300 SH   DFND 2 2,300 0 0
WALMART INC COM 931142103   5,680,445 36,032 SH   DFND 1 36,032 0 0
WELLS FARGO CO NEW COM 949746101   18,551,363 376,907 SH   DFND 1 376,907 0 0
WINNEBAGO INDS INC NOTE 1.500% 4/0 974637AB6   5,645,790 4,500,000 PRN   DFND 1 4,500,000 0 0
WIX COM LTD SHS M98068105   9,696,928 78,824 SH   DFND 1 78,824 0 0
WOLFSPEED INC NOTE 1.750% 5/0 225447AD3   12,793,200 11,200,000 PRN   DFND 1 11,200,000 0 0
WOLFSPEED INC COM 977852102   24,121,944 554,400 SH   DFND 1,2 554,400 0 0
WORKDAY INC CL A 98138H101   59,420,535 215,245 SH   DFND 1 215,245 0 0
XENON PHARMACEUTICALS INC COM 98420N105   141,248,886 3,066,628 SH   DFND 1 3,066,628 0 0
Y-MABS THERAPEUTICS INC COM 984241109   14,027,867 2,056,872 SH   DFND 1 2,056,872 0 0
ZAI LAB LTD ADR 98887Q104   2,786,594 101,961 SH   DFND 1 101,961 0 0
ZILLOW GROUP INC NOTE 2.750% 5/1 98954MAH4   11,056,100 10,000,000 PRN   DFND 1 10,000,000 0 0
ZILLOW GROUP INC NOTE 1.375% 9/0 98954MAG6   5,461,480 4,000,000 PRN   DFND 1 4,000,000 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102   24,282,801 199,530 SH   DFND 1 199,530 0 0
ZSCALER INC NOTE 0.125% 7/0 98980GAB8   5,773,986 3,800,000 PRN   DFND 1 3,800,000 0 0
ZSCALER INC COM 98980G102   97,743,631 441,161 SH   DFND 1 441,161 0 0