0001172661-24-000951.txt : 20240214 0001172661-24-000951.hdr.sgml : 20240214 20240214090152 ACCESSION NUMBER: 0001172661-24-000951 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20231231 FILED AS OF DATE: 20240214 DATE AS OF CHANGE: 20240214 EFFECTIVENESS DATE: 20240214 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Polar Capital Holdings Plc CENTRAL INDEX KEY: 0001837309 ORGANIZATION NAME: IRS NUMBER: 000000000 STATE OF INCORPORATION: X0 FISCAL YEAR END: 0331 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-20910 FILM NUMBER: 24632856 BUSINESS ADDRESS: STREET 1: 16 PALACE STREET CITY: LONDON STATE: X0 ZIP: SW1E 5JD BUSINESS PHONE: 02072272700 MAIL ADDRESS: STREET 1: 16 PALACE STREET CITY: LONDON STATE: X0 ZIP: SW1E 5JD 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false true false 0001837309 XXXXXXXX 12-31-2023 12-31-2023 false Polar Capital Holdings Plc

16 Palace Street London X0 SW1E 5JD

13F HOLDINGS REPORT 028-20910 000136133 801-64644 N Samir Ayub 44-0-20-7227-2700 /s/ Samir Ayub London X0 02-14-2024 2 276 16323531320 1 0001439303 028-13167 Polar Capital LLP 2 0001965543 028-23030 Polar Capital (Switzerland) AG INFORMATION TABLE 2 infotable.xml ABBOTT LABS COM 002824100 35772750 325000 SH DFND 1 325000 0 0 ABBVIE INC COM 00287Y109 56069386 361808 SH DFND 1 361808 0 0 ACADIA HEALTHCARE COMPANY IN COM 00404A109 84955677 1092537 SH DFND 1 1092537 0 0 ADDUS HOMECARE CORP COM 006739106 31214313 336180 SH DFND 1 336180 0 0 ADOBE INC COM 00724F101 114312736 191607 SH DFND 1 191607 0 0 ADVANCED MICRO DEVICES INC COM 007903107 497368416 3374048 SH DFND 1 3374048 0 0 AFFILIATED MANAGERS GROUP IN COM 008252108 10142263 66981 SH DFND 1 66981 0 0 AFLAC INC COM 001055102 40012500 485000 SH DFND 1 485000 0 0 AIR PRODS & CHEMS INC COM 009158106 8788980 32100 SH DFND 1,2 32100 0 0 AKAMAI TECHNOLOGIES INC NOTE 0.125% 5/0 00971TAJ0 12730800 10000000 PRN DFND 1 10000000 0 0 AKOYA BIOSCIENCES INC COM 00974H104 7709209 1579756 SH DFND 1 1579756 0 0 ALBEMARLE CORP COM 012653101 5605824 38800 SH DFND 1,2 38800 0 0 ALCON AG ORD SHS H01301128 23407974 340473 SH DFND 1 340473 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 35410850 185000 SH DFND 1 185000 0 0 ALNYLAM PHARMACEUTICALS INC NOTE 1.000% 9/1 02043QAB3 3950480 4000000 PRN DFND 1 4000000 0 0 ALPHABET INC CAP STK CL C 02079K107 347510408 2465837 SH DFND 1 2465837 0 0 ALPHABET INC CAP STK CL A 02079K305 338077598 2420199 SH DFND 1 2420199 0 0 AMAZON COM INC COM 023135106 313349205 2062322 SH DFND 1 2062322 0 0 AMDOCS LTD SHS G02602103 21759367 247575 SH DFND 1 247575 0 0 AMERICAN EXPRESS CO COM 025816109 10089945 53859 SH DFND 1 53859 0 0 AMGEN INC COM 031162100 70562596 244992 SH DFND 1 244992 0 0 ANALOG DEVICES INC COM 032654105 30663621 154430 SH DFND 1,2 154430 0 0 ANSYS INC COM 03662Q105 9453024 26050 SH DFND 1,2 26050 0 0 AON PLC SHS CL A G0403H108 59659100 205000 SH DFND 1 205000 0 0 APELLIS PHARMACEUTICALS INC COM 03753U106 63058918 1053440 SH DFND 1 1053440 0 0 APPLE INC COM 037833100 553351553 2880033 SH DFND 1 2880033 0 0 APTARGROUP INC COM 038336103 18160767 146908 SH DFND 1 146908 0 0 APTIV PLC SHS G6095L109 358880 4000 SH DFND 2 4000 0 0 ARCH CAP GROUP LTD ORD G0450A105 233444870 3143192 SH DFND 1 3143192 0 0 ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 20341532 6297688 SH DFND 1 6297688 0 0 ARES CAPITAL CORP COM 04010L103 3925319 195972 SH DFND 1 195972 0 0 ARES MANAGEMENT CORPORATION CL A COM STK 03990B101 8180507 68790 SH DFND 1 68790 0 0 ARISTA NETWORKS INC COM 040413106 185726012 788612 SH DFND 1 788612 0 0 ARM HOLDINGS PLC SPONSORED ADR 042068205 71308597 1005763 SH Call DFND 1 1005763 0 0 ARRAY TECHNOLOGIES INC NOTE 1.000%12/0 04271TAB6 14139773 14350000 PRN DFND 1 14350000 0 0 ASCENDIS PHARMA A/S NOTE 2.250% 4/0 04351PAD3 12361800 12000000 PRN DFND 1 12000000 0 0 ATLASSIAN CORPORATION CL A 049468101 10339774 43470 SH DFND 1 43470 0 0 AUTODESK INC COM 052769106 12880092 52900 SH DFND 1,2 52900 0 0 AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 95335162 6751782 SH DFND 1 6751782 0 0 AXON ENTERPRISE INC COM 05464C101 57245411 221598 SH DFND 1 221598 0 0 BAIDU INC SPON ADR REP A 056752108 16452641 138153 SH DFND 1 138153 0 0 BAKER HUGHES COMPANY CL A 05722G100 8359847 244583 SH DFND 1 244583 0 0 BANK AMERICA CORP COM 060505104 16372475 486263 SH DFND 1 486263 0 0 BECTON DICKINSON & CO COM 075887109 14996520 61504 SH DFND 1 61504 0 0 BERKLEY W R CORP COM 084423102 134898400 1907500 SH DFND 1 1907500 0 0 BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 55205975 154786 SH DFND 1 154786 0 0 BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 18161993 1004535 SH DFND 1 1004535 0 0 BIO RAD LABS INC CL A 090572207 17024698 52726 SH DFND 1 52726 0 0 BIOCERES CROP SOLUTIONS CORP SHS G1117K114 16421808 1196053 SH DFND 1 1196053 0 0 BIOGEN INC COM 09062X103 77631000 300000 SH DFND 1 300000 0 0 BLACKLINE INC NOTE 3/1 09239BAD1 12328034 13950000 PRN DFND 1 13950000 0 0 BLACKROCK INC COM 09247X101 8816960 10861 SH DFND 1 10861 0 0 BLOCK INC CL A 852234103 17488526 226096 SH DFND 1 226096 0 0 BLUEPRINT MEDICINES CORP COM 09627Y109 79787600 865000 SH DFND 1 865000 0 0 BOOKING HOLDINGS INC COM 09857L108 18764794 5290 SH DFND 1 5290 0 0 BORGWARNER INC COM 099724106 286800 8000 SH DFND 2 8000 0 0 BOSTON SCIENTIFIC CORP COM 101137107 58567600 1013105 SH DFND 1 1013105 0 0 BRAZE INC COM CL A 10576N102 11123350 209361 SH DFND 1 209361 0 0 BROADCOM INC COM 11135F101 80470463 72090 SH DFND 1 72090 0 0 BRUKER CORP COM 116794108 203613 2771 SH DFND 1 2771 0 0 CABALETTA BIO INC COM 12674W109 28375000 1250000 SH DFND 1 1250000 0 0 CADENCE DESIGN SYSTEM INC COM 127387108 95924628 352185 SH DFND 1 352185 0 0 CANADIAN NAT RES LTD COM 136385101 10898932 141386 SH DFND 1 141386 0 0 CANNAE HLDGS INC COM 13765N107 9289413 476136 SH DFND 1 476136 0 0 CARRIER GLOBAL CORPORATION COM 14448C104 3274650 57000 SH DFND 1,2 57000 0 0 CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 124368644 3135871 SH DFND 1 3135871 0 0 CENOVUS ENERGY INC COM 15135U109 18187533 923339 SH DFND 1 923339 0 0 CENTENE CORP DEL COM 15135B101 21554517 290453 SH DFND 1 290453 0 0 CERIDIAN HCM HLDG INC NOTE 0.250% 3/1 15677JAD0 10158748 11288000 PRN DFND 1 11288000 0 0 CERUS CORP COM 157085101 57326 26540 SH DFND 1 26540 0 0 CHEMED CORP NEW COM 16359R103 4797874 8205 SH DFND 1 8205 0 0 CHEWY INC CL A 16679L109 6265636 265156 SH DFND 1 265156 0 0 CHUBB LIMITED COM H1467J104 204245466 903741 SH DFND 1 903741 0 0 CLOUDFLARE INC CL A COM 18915M107 60798367 730223 SH DFND 1 730223 0 0 COCA-COLA EUROPACIFIC PARTNE SHS G25839104 10337893 154898 SH DFND 1 154898 0 0 COGNEX CORP COM 192422103 22016765 527474 SH DFND 1,2 527474 0 0 COHERENT CORP COM 19247G107 6812010 156490 SH DFND 1 156490 0 0 CORE & MAIN INC CL A 21874C102 13358980 330586 SH DFND 1 330586 0 0 CRH PLC ORD G25508105 41786265 604197 SH DFND 1 604197 0 0 CROWDSTRIKE HLDGS INC CL A 22788C105 191848469 751404 SH DFND 1 751404 0 0 CYBERARK SOFTWARE LTD SHS M2682V108 107270756 489709 SH DFND 1 489709 0 0 CYTOKINETICS INC NOTE 3.500% 7/0 23282WAC4 3002064 1700000 PRN DFND 1 1700000 0 0 CYTOKINETICS INC COM NEW 23282W605 118309838 1417054 SH DFND 1 1417054 0 0 DATADOG INC NOTE 0.125% 6/1 23804LAB9 12222438 8750000 PRN DFND 1 8750000 0 0 DATADOG INC CL A COM 23804L103 77982159 642463 SH DFND 1 642463 0 0 DAY ONE BIOPHARMACEUTICALS I COM 23954D109 20221000 1385000 SH DFND 1 1385000 0 0 DECIPHERA PHARMACEUTICALS IN COM 24344T101 29840500 1850000 SH DFND 1 1850000 0 0 DEERE & CO COM 244199105 4008297 10024 SH DFND 1 10024 0 0 DENALI THERAPEUTICS INC COM 24823R105 9714277 452669 SH DFND 1 452669 0 0 DEXCOM INC COM 252131107 30360728 244667 SH DFND 1 244667 0 0 DISC MEDICINE INC COM 254604101 31589810 546915 SH DFND 1 546915 0 0 DOORDASH INC CL A 25809K105 68210960 689766 SH DFND 1 689766 0 0 DOUBLEVERIFY HLDGS INC COM 25862V105 11762832 319816 SH DFND 1 319816 0 0 DROPBOX INC NOTE 3/0 26210CAD6 4024800 4000000 PRN DFND 1 4000000 0 0 DYNATRACE INC COM NEW 268150109 21807255 398743 SH DFND 1 398743 0 0 EAST WEST BANCORP INC COM 27579R104 8495352 118073 SH DFND 1 118073 0 0 EATON CORP PLC SHS G29183103 3087553 12821 SH DFND 1 12821 0 0 ELASTIC N V ORD SHS N14506104 97622994 866220 SH DFND 1 866220 0 0 ELEVANCE HEALTH INC COM 036752103 56113754 118996 SH DFND 1 118996 0 0 ELI LILLY & CO COM 532457108 64436560 110541 SH DFND 1 110541 0 0 EMERSON ELEC CO COM 291011104 2680566 27541 SH DFND 1 27541 0 0 ENERSYS COM 29275Y102 6935952 68700 SH DFND 1,2 68700 0 0 ENPHASE ENERGY INC COM 29355A107 13874700 105000 SH DFND 1 105000 0 0 ENVISTA HOLDINGS CORPORATION COM 29415F104 12112742 503439 SH DFND 1 503439 0 0 ESSENT GROUP LTD COM G3198U102 125916750 2387500 SH DFND 1 2387500 0 0 ESTABLISHMENT LABS HLDGS INC COM G31249108 5864577 226519 SH DFND 1 226519 0 0 EVEREST GROUP LTD COM G3223R108 102884001 290978 SH DFND 1 290978 0 0 EXACT SCIENCES CORP NOTE 0.375% 3/1 30063PAB1 9721600 10000000 PRN DFND 1 10000000 0 0 EXELIXIS INC COM 30161Q104 7259518 302606 SH DFND 1 302606 0 0 FABRINET SHS G3323L100 108155784 568254 SH DFND 1 568254 0 0 FERGUSON PLC NEW SHS G3421J106 1847267493 184295 SH DFND 1 184295 0 0 FIDELITY NATL INFORMATION SV COM 31620M106 11642047 193808 SH DFND 1 193808 0 0 FIRST AMERN FINL CORP COM 31847R102 45108000 700000 SH DFND 1 700000 0 0 FISERV INC COM 337738108 17651248 132876 SH DFND 1 132876 0 0 GLOBANT S A COM L44385109 40101534 168508 SH DFND 1 168508 0 0 GOLUB CAP BDC INC COM 38173M102 3169188 209880 SH DFND 1 209880 0 0 H WORLD GROUP LTD SPONSORED ADS 44332N106 3155465 94362 SH DFND 1 94362 0 0 HAGERTY INC CL A COM 405166109 38415000 4925000 SH DFND 1 4925000 0 0 HCA HEALTHCARE INC COM 40412C101 99146294 366286 SH DFND 1 366286 0 0 HOLOGIC INC COM 436440101 5402978 75619 SH DFND 1 75619 0 0 HUBSPOT INC COM 443573100 123825118 213293 SH DFND 1 213293 0 0 HUMANA INC COM 444859102 12926265 28235 SH DFND 1 28235 0 0 HYATT HOTELS CORP COM CL A 448579102 12674939 97193 SH DFND 1 97193 0 0 ICON PLC SHS G4705A100 14299564 50516 SH DFND 1 50516 0 0 IMMUNOCORE HLDGS PLC ADS 45258D105 34248816 501300 SH DFND 1 501300 0 0 IMPERIAL OIL LTD COM NEW 453038408 13538719 201063 SH DFND 1 201063 0 0 IMPINJ INC NOTE 1.125% 5/1 453204AD1 3578447 3280000 PRN DFND 1 3280000 0 0 INCYTE CORP COM 45337C102 5651100 90000 SH DFND 1 90000 0 0 INSMED INC COM PAR $.01 457669307 15627482 504275 SH DFND 1 504275 0 0 INSULET CORP COM 45784P101 24078488 110971 SH DFND 1 110971 0 0 INSULET CORP NOTE 0.375% 9/0 45784PAK7 3446760 3000000 PRN DFND 1 3000000 0 0 INTERACTIVE BROKERS GROUP IN COM CL A 45841N107 19670844 237284 SH DFND 1 237284 0 0 INTERCONTINENTAL EXCHANGE IN COM 45866F104 32916866 256302 SH DFND 1 256302 0 0 INTRA-CELLULAR THERAPIES INC COM 46116X101 66516717 928745 SH DFND 1 928745 0 0 INTUIT COM 461202103 24713686 39540 SH DFND 1 39540 0 0 INTUITIVE SURGICAL INC COM NEW 46120E602 107537886 318763 SH DFND 1 318763 0 0 IQVIA HLDGS INC COM 46266C105 19659664 84967 SH DFND 1 84967 0 0 IRHYTHM TECHNOLOGIES INC COM 450056106 336855 3147 SH DFND 1 3147 0 0 JAMES RIV GROUP LTD COM G5005R107 11665500 1262500 SH DFND 1 1262500 0 0 JAZZ INVESTMENTS I LTD NOTE 2.000% 6/1 472145AF8 4037200 4000000 PRN DFND 1 4000000 0 0 JFROG LTD ORD SHS M6191J100 19413303 560916 SH DFND 1 560916 0 0 JOHNSON & JOHNSON COM 478160104 7951420 50730 SH DFND 1 50730 0 0 JPMORGAN CHASE & CO COM 46625H100 44204737 259875 SH DFND 1 259875 0 0 KE HLDGS INC SPONSORED ADS 482497104 166039 10243 SH DFND 1 10243 0 0 KLA CORP COM NEW 482480100 137147853 235933 SH DFND 1 235933 0 0 KLAVIYO INC COM SER A 49845K101 6794516 244583 SH DFND 1 244583 0 0 LANTHEUS HLDGS INC NOTE 2.625%12/1 516544AB9 2793950 2500000 PRN DFND 1 2500000 0 0 LATTICE SEMICONDUCTOR CORP COM 518415104 75833532 1099196 SH DFND 1,2 1099196 0 0 LEGEND BIOTECH CORP SPONSORED ADS 52490G102 82461541 1370476 SH DFND 1 1370476 0 0 LENNOX INTL INC COM 526107107 11568392 25850 SH DFND 1,2 25850 0 0 LIBERTY MEDIA CORP DEL NOTE 2.250% 8/1 531229AQ5 1827864 1800000 PRN DFND 1 1800000 0 0 LIBERTY MEDIA CORP DEL COM LBTY ONE S C 531229755 12656050 200476 SH DFND 1 200476 0 0 LIFESTANCE HEALTH GROUP INC COM 53228F101 110677 14135 SH DFND 1 14135 0 0 LINDE PLC SHS G54950103 35451255 86317 SH DFND 1,2 86317 0 0 LITTELFUSE INC COM 537008104 12698933 47462 SH DFND 1 47462 0 0 LIVANOVA PLC SHS G5509L101 8983668 173631 SH DFND 1 173631 0 0 LIVENT CORP COM 53814L108 6023300 335000 SH DFND 1,2 335000 0 0 LONGBOARD PHARMACEUTICALS IN COM 54300N103 6030000 1000000 SH DFND 1 1000000 0 0 MAKEMYTRIP LIMITED MAURITIUS SHS V5633W109 43007935 915452 SH DFND 1 915452 0 0 MARKEL GROUP INC COM 570535104 120691500 85000 SH DFND 1 85000 0 0 MARRIOTT INTL INC NEW CL A 571903202 8359430 37069 SH DFND 1 37069 0 0 MARSH & MCLENNAN COS INC COM 571748102 180930208 954928 SH DFND 1 954928 0 0 MARVELL TECHNOLOGY INC COM 573874104 25462882 422200 SH DFND 1,2 422200 0 0 MASTERCARD INCORPORATED CL A 57636Q104 66624701 156209 SH DFND 1 156209 0 0 MCKESSON CORP COM 58155Q103 74396719 160691 SH DFND 1 160691 0 0 MERCADOLIBRE INC COM 58733R102 49571086 31543 SH DFND 1 31543 0 0 MERIT MED SYS INC COM 589889104 36334858 478342 SH DFND 1 478342 0 0 META PLATFORMS INC CL A 30303M102 326817639 923318 SH DFND 1 923318 0 0 MICRON TECHNOLOGY INC COM 595112103 165983398 1944966 SH DFND 1 1944966 0 0 MICROSOFT CORP COM 594918104 743214481 1976424 SH DFND 1 1976424 0 0 MIRUM PHARMACEUTICALS INC COM 604749101 18450000 625000 SH DFND 1 625000 0 0 MKS INSTRS INC COM 55306N104 15369498 149407 SH DFND 1 149407 0 0 MONDAY COM LTD SHS M7S64H106 58547138 311736 SH DFND 1 311736 0 0 MONGODB INC CL A 60937P106 142475639 348479 SH DFND 1 348479 0 0 MONOLITHIC PWR SYS INC COM 609839105 138909741 220219 SH DFND 1,2 220219 0 0 MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104 56592375 937115 SH DFND 1 937115 0 0 MORGAN STANLEY COM NEW 617446448 11114374 119189 SH DFND 1 119189 0 0 MP MATERIALS CORP COM CL A 553368101 11860375 597500 SH DFND 1,2 597500 0 0 MSCI INC COM 55354G100 5297878 9366 SH DFND 1 9366 0 0 NANOSTRING TECHNOLOGIES INC COM 63009R109 2974890 3975000 SH DFND 1 3975000 0 0 NATERA INC COM 632307104 350784 5600 SH DFND 1 5600 0 0 NETFLIX INC COM 64110L106 127038677 260924 SH DFND 1 260924 0 0 NEUROCRINE BIOSCIENCES INC COM 64125C109 110129356 835833 SH DFND 1 835833 0 0 NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES N62509109 10161818 909742 SH Call DFND 1 909742 0 0 NIO INC SPON ADS 62914V106 4988500 550000 SH DFND 1,2 550000 0 0 NORFOLK SOUTHN CORP COM 655844108 10425540 44105 SH DFND 1 44105 0 0 NU HLDGS LTD ORD SHS CL A G6683N103 190449 22863 SH DFND 1 22863 0 0 NUTANIX INC NOTE 0.250%10/0 67059NAH1 25387703 24510000 PRN DFND 1 24510000 0 0 NVIDIA CORPORATION COM 67066G104 722038684 1458016 SH DFND 1 1458016 0 0 NXP SEMICONDUCTORS N V COM N6596X109 11024640 48000 SH DFND 1,2 48000 0 0 OLEMA PHARMACEUTICALS INC COM 68062P106 10522500 750000 SH DFND 1 750000 0 0 ON SEMICONDUCTOR CORP COM 682189105 22394393 268100 SH DFND 1,2 268100 0 0 PALO ALTO NETWORKS INC COM 697435105 114034224 386714 SH DFND 1 386714 0 0 PATRICK INDS INC NOTE 1.750%12/0 703343AG8 3448500 3000000 PRN DFND 1 3000000 0 0 PAYPAL HLDGS INC COM 70450Y103 206583 3364 SH DFND 1 3364 0 0 PDD HOLDINGS INC SPONSORED ADS 722304102 57262515 391378 SH DFND 1 391378 0 0 PENUMBRA INC COM 70975L107 32089964 127574 SH DFND 1 127574 0 0 PINTEREST INC CL A 72352L106 85090844 2297269 SH DFND 1 2297269 0 0 PLIANT THERAPEUTICS INC COM 729139105 36491650 2015000 SH DFND 1 2015000 0 0 POWER INTEGRATIONS INC COM 739276103 1190595 14500 SH DFND 1,2 14500 0 0 PRIVIA HEALTH GROUP INC COM 74276R102 226569 9838 SH DFND 1 9838 0 0 PROASSURANCE CORP COM 74267C106 29820875 2162500 SH DFND 1 2162500 0 0 PROGRESSIVE CORP COM 743315103 93577000 587500 SH DFND 1 587500 0 0 PURE STORAGE INC CL A 74624M102 106634669 2990316 SH DFND 1 2990316 0 0 QIAGEN NV SHS NEW N72482123 21909806 440325 SH DFND 1 440325 0 0 QORVO INC COM 74736K101 9459240 84000 SH DFND 1,2 84000 0 0 QUALCOMM INC COM 747525103 103860828 718114 SH DFND 1 718114 0 0 R1 RCM INC COM 77634L105 127125 12027 SH DFND 1 12027 0 0 RAMBUS INC DEL COM 750917106 103161308 1511521 SH DFND 1 1511521 0 0 REGENERON PHARMACEUTICALS COM 75886F107 173767042 197847 SH DFND 1 197847 0 0 REINSURANCE GRP OF AMERICA I COM NEW 759351604 78867750 487500 SH DFND 1 487500 0 0 RENAISSANCERE HLDGS LTD COM G7496G103 214701732 1095417 SH DFND 1 1095417 0 0 REVANCE THERAPEUTICS INC COM 761330109 27857611 3169239 SH DFND 1 3169239 0 0 RHYTHM PHARMACEUTICALS INC COM 76243J105 80447500 1750000 SH DFND 1 1750000 0 0 RLI CORP COM 749607107 34611200 260000 SH DFND 1 260000 0 0 ROBLOX CORP CL A 771049103 20330815 444681 SH DFND 1 444681 0 0 ROCKWELL AUTOMATION INC COM 773903109 9789745 31531 SH DFND 1 31531 0 0 ROYAL BK CDA COM 780087102 13129949 109836 SH DFND 1 109836 0 0 RYAN SPECIALTY HOLDINGS INC CL A 78351F107 55388250 1287500 SH DFND 1 1287500 0 0 S&P GLOBAL INC COM 78409V104 16282500 36962 SH DFND 1 36962 0 0 SABRE CORP COM 78573M104 4011590 911725 SH DFND 1 911725 0 0 SALESFORCE INC COM 79466L302 72209037 274413 SH DFND 1 274413 0 0 SAREPTA THERAPEUTICS INC NOTE 1.250% 9/1 803607AD2 3554040 3500000 PRN DFND 1 3500000 0 0 SCHLUMBERGER LTD COM STK 806857108 7944843 152668 SH DFND 1 152668 0 0 SCHOLAR ROCK HLDG CORP COM 80706P103 55284634 2940672 SH DFND 1 2940672 0 0 SEA LTD SPONSORD ADS 81141R100 17508150 432300 SH DFND 1 432300 0 0 SERVICENOW INC COM 81762P102 170348162 241119 SH DFND 1 241119 0 0 SHOCKWAVE MED INC COM 82489T104 24183588 126908 SH DFND 1 126908 0 0 SHOPIFY INC CL A 82509L107 156089944 2003722 SH DFND 1 2003722 0 0 SNOWFLAKE INC CL A 833445109 110389280 554720 SH DFND 1 554720 0 0 SPOTIFY TECHNOLOGY S A SHS L8681T102 22646725 120519 SH DFND 1 120519 0 0 SPYRE THERAPEUTICS INC COM NEW 00773J202 10760000 500000 SH DFND 1 500000 0 0 SS&C TECHNOLOGIES HLDGS INC COM 78467J100 14869896 243330 SH DFND 1 243330 0 0 SSR MINING IN NOTE 2.500% 4/0 784730AB9 2412629 2549000 PRN DFND 1 2549000 0 0 STANDARD BIOTOOLS INC COM 34385P108 125053 56585 SH DFND 1 56585 0 0 STEREOTAXIS INC COM NEW 85916J409 122022 69727 SH DFND 1 69727 0 0 STRYKER CORPORATION COM 863667101 8725965 29139 SH DFND 1 29139 0 0 SUPERNUS PHARMACEUTICALS INC COM 868459108 56125223 1939365 SH DFND 1 1939365 0 0 SYNOPSYS INC COM 871607107 135720493 263581 SH DFND 1 263581 0 0 TAYSHA GENE THERAPIES INC COM SHS 877619106 4458469 2518909 SH DFND 1 2518909 0 0 TECK RESOURCES LTD CL B 878742204 12237545 289509 SH DFND 1 289509 0 0 TENET HEALTHCARE CORP COM NEW 88033G407 20918003 276803 SH DFND 1 276803 0 0 TESLA INC COM 88160R101 130204762 524005 SH DFND 1 524005 0 0 THE TRADE DESK INC COM CL A 88339J105 69975919 972428 SH DFND 1 972428 0 0 T-MOBILE US INC COM 872590104 13920011 86821 SH DFND 1 86821 0 0 TORONTO DOMINION BK ONT COM NEW 891160509 7269848 95178 SH DFND 1 95178 0 0 TRAVELERS COMPANIES INC COM 89417E109 104105261 546513 SH DFND 1 546513 0 0 TRIMBLE INC COM 896239100 351120 6600 SH DFND 2 6600 0 0 TRUPANION INC COM 898202106 38137500 1250000 SH DFND 1 1250000 0 0 UBER TECHNOLOGIES INC COM 90353T100 79328081 1288421 SH DFND 1,2 1288421 0 0 UNION PAC CORP COM 907818108 19781744 80538 SH DFND 1 80538 0 0 UNITED RENTALS INC COM 911363109 23373173 40761 SH DFND 1 40761 0 0 US BANCORP DEL COM NEW 902973304 11062498 255603 SH DFND 1 255603 0 0 US FOODS HLDG CORP COM 912008109 23681451 521503 SH DFND 1 521503 0 0 VERA THERAPEUTICS INC CL A 92337R101 11150500 725000 SH DFND 1 725000 0 0 VERTEX PHARMACEUTICALS INC COM 92532F100 71205750 175000 SH DFND 1 175000 0 0 VERTIV HOLDINGS CO COM CL A 92537N108 13928700 290000 SH DFND 1,2 290000 0 0 VIRIDIAN THERAPEUTICS INC COM 92790C104 21342592 979917 SH DFND 1 979917 0 0 VIRTU FINL INC CL A 928254101 3241600 160000 SH DFND 1 160000 0 0 VISA INC COM CL A 92826C839 64767009 248769 SH DFND 1 248769 0 0 VISTEON CORP COM NEW 92839U206 287270 2300 SH DFND 2 2300 0 0 WALMART INC COM 931142103 5680445 36032 SH DFND 1 36032 0 0 WELLS FARGO CO NEW COM 949746101 18551363 376907 SH DFND 1 376907 0 0 WINNEBAGO INDS INC NOTE 1.500% 4/0 974637AB6 5645790 4500000 PRN DFND 1 4500000 0 0 WIX COM LTD SHS M98068105 9696928 78824 SH DFND 1 78824 0 0 WOLFSPEED INC NOTE 1.750% 5/0 225447AD3 12793200 11200000 PRN DFND 1 11200000 0 0 WOLFSPEED INC COM 977852102 24121944 554400 SH DFND 1,2 554400 0 0 WORKDAY INC CL A 98138H101 59420535 215245 SH DFND 1 215245 0 0 XENON PHARMACEUTICALS INC COM 98420N105 141248886 3066628 SH DFND 1 3066628 0 0 Y-MABS THERAPEUTICS INC COM 984241109 14027867 2056872 SH DFND 1 2056872 0 0 ZAI LAB LTD ADR 98887Q104 2786594 101961 SH DFND 1 101961 0 0 ZILLOW GROUP INC NOTE 2.750% 5/1 98954MAH4 11056100 10000000 PRN DFND 1 10000000 0 0 ZILLOW GROUP INC NOTE 1.375% 9/0 98954MAG6 5461480 4000000 PRN DFND 1 4000000 0 0 ZIMMER BIOMET HOLDINGS INC COM 98956P102 24282801 199530 SH DFND 1 199530 0 0 ZSCALER INC NOTE 0.125% 7/0 98980GAB8 5773986 3800000 PRN DFND 1 3800000 0 0 ZSCALER INC COM 98980G102 97743631 441161 SH DFND 1 441161 0 0