SCHEDULE 13G/A 0001214659-24-006425 0001856079 XXXXXXXX LIVE 1 Common Stock, $0.0001 par value per share 09/30/2025 0001835597 PepGen Inc. 713317105 321 Harrison Avenue 8th Floor BOSTON MA 02118 Rule 13d-1(c) Oxford Science Enterprises plc X0 4955388.00 0.00 4955388.00 0.00 4955388.00 7.2 CO Row 11 is based on the quotient obtained by dividing (a) the aggregate number of Common Stock beneficially owned by Oxford Science Enterprises plc by (b) the 68,737,224 total shares of Common Stock outstanding as of September 26, 2025, as disclosed by the Issuer in its prospectus supplement dated September 24, 2025, and filed with the SEC on September 25, 2025. PepGen Inc. 321 Harrison Avenue, 8th Floor, BOSTON, MASSACHUSETTS, 02118 Oxford Science Enterprises plc (the "Reporting Person") 46 Woodstock Road, Oxford OX2 6HT, United Kingdom England, United Kingdom Y 4,955,388 7.21% 4,955,388 0 4,955,388 0 Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11. Oxford Science Enterprises plc /s/ Jim Wilkinson 10/01/2025