<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
<headerData>
<submissionType>SCHEDULE 13G/A</submissionType>
<previousAccessionNumber>0001140361-24-046970</previousAccessionNumber>
<filerInfo>
<filer>
<filerCredentials>
<cik>0001858703</cik>
<ccc>XXXXXXXX</ccc>
</filerCredentials>
</filer>
<liveTestFlag>LIVE</liveTestFlag>



</filerInfo>
</headerData>
<formData>
<coverPageHeader>
<amendmentNo>1</amendmentNo>
<securitiesClassTitle>Common Stock, $0.001 par value</securitiesClassTitle>
<eventDateRequiresFilingThisStatement>09/30/2025</eventDateRequiresFilingThisStatement>
<issuerInfo>
<issuerCik>0001835579</issuerCik>
<issuerName>ImageneBio, Inc.</issuerName>
<issuerCusip>45175G207</issuerCusip>
<issuerPrincipalExecutiveOfficeAddress>
<com:street1>12526 High Bluff Drive</com:street1>
<com:street2>Suite 345</com:street2>
<com:city>San Diego</com:city>
<com:stateOrCountry>CA</com:stateOrCountry>
<com:zipCode>92130</com:zipCode>
</issuerPrincipalExecutiveOfficeAddress>
</issuerInfo>
<designateRulesPursuantThisScheduleFiled>
<designateRulePursuantThisScheduleFiled>Rule 13d-1(b)</designateRulePursuantThisScheduleFiled>
</designateRulesPursuantThisScheduleFiled>
</coverPageHeader>
<coverPageHeaderReportingPersonDetails>

<reportingPersonName>Blue Owl Capital Holdings LP</reportingPersonName>
<citizenshipOrOrganization>DE</citizenshipOrOrganization>
<reportingPersonBeneficiallyOwnedNumberOfShares>
<soleVotingPower>540924</soleVotingPower>
<sharedVotingPower>0</sharedVotingPower>
<soleDispositivePower>540924</soleDispositivePower>
<sharedDispositivePower>0</sharedDispositivePower>
</reportingPersonBeneficiallyOwnedNumberOfShares>
<reportingPersonBeneficiallyOwnedAggregateNumberOfShares>540924</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
<aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
<classPercent>4.84</classPercent>
<typeOfReportingPerson>PN</typeOfReportingPerson>
<comments>The reported percentage is calculated based on 11,181,676 shares of Common Stock outstanding as of July 25, 2025, as reported in the Issuer's registration statement on Form S-1 filed with the Securities and Exchange Commission on September 8, 2025.</comments>
</coverPageHeaderReportingPersonDetails>
<items>
<item1>
<issuerName>ImageneBio, Inc.</issuerName>
<issuerPrincipalExecutiveOfficeAddress>12526 High Bluff Drive, Suite 345, San Diego, California, 92130</issuerPrincipalExecutiveOfficeAddress>
</item1>
<item2>
<filingPersonName>This statement is filed by the Blue Owl Capital Holdings LP, referred to herein as the "Reporting Person."</filingPersonName>
<principalBusinessOfficeOrResidenceAddress>399 Park Avenue
New York, New York 10022</principalBusinessOfficeOrResidenceAddress>
<citizenship>See response to Item 4 on the cover page.</citizenship>
</item2>
<item3>
<notApplicableFlag>N</notApplicableFlag>
<typeOfPersonFiling>IA</typeOfPersonFiling>
</item3>
<item4>
<amountBeneficiallyOwned>See response to Item 9 on the cover page.
The filing of this statement shall not be deemed an admission by the Reporting Person of beneficial ownership of the reported securities for purposes of Section 13(d) or Section 13(g) or any other purpose.</amountBeneficiallyOwned>
<classPercent>See response to Item 11 on the cover page.</classPercent>
<numberOfSharesPersonHas>
<solePowerOrDirectToVote>See response to Item 5 on the cover page.</solePowerOrDirectToVote>
<sharedPowerOrDirectToVote>See response to Item 6 on the cover page.</sharedPowerOrDirectToVote>
<solePowerOrDirectToDispose>See response to Item 7 on the cover page.</solePowerOrDirectToDispose>
<sharedPowerOrDirectToDispose>See response to Item 8 on the cover page.</sharedPowerOrDirectToDispose>
</numberOfSharesPersonHas>
</item4>
<item5>
<notApplicableFlag>N</notApplicableFlag>
<classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
</item5>
<item6>
<notApplicableFlag>Y</notApplicableFlag>
</item6>
<item7>
<notApplicableFlag>Y</notApplicableFlag>
</item7>
<item8>
<notApplicableFlag>Y</notApplicableFlag>
</item8>
<item9>
<notApplicableFlag>Y</notApplicableFlag>
</item9>
<item10>
<notApplicableFlag>N</notApplicableFlag>
<certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
</item10>
</items>
<signatureInformation>
<reportingPersonName>Blue Owl Capital Holdings LP</reportingPersonName>
<signatureDetails>
<signature>/s/ Karen Hager</signature>
<title>Karen Hager / Chief Compliance Officer</title>
<date>11/14/2025</date>
</signatureDetails>
</signatureInformation>
</formData>
</edgarSubmission>
