X0508 4 2025-12-03 0 0001822791 Clene Inc. CLNN 0001835544 Ugwumba Chidozie 609 SW 8TH STREET SUITE 510 BENTONVILLE AR 72712 0 0 1 0 0 Common Stock 2025-12-03 4 S 0 56577 7.86 D 594368 I By Symbiosis II, LLC Common Stock 2025-12-04 4 S 0 72748 6.73 D 521620 I By Symbiosis II, LLC Common Stock 2025-12-05 4 S 0 37235 5.94 D 484385 I By Symbiosis II, LLC Common Stock 2025-12-08 4 S 0 21463 5.7 D 462922 I By Symbiosis II, LLC Common Stock 2025-12-09 4 S 0 15031 5.95 D 447891 I By Symbiosis II, LLC Common Stock 2025-12-10 4 S 0 9921 6.42 D 437970 I By Symbiosis II, LLC Common Stock 2025-12-11 4 S 0 10907 6.81 D 427063 I By Symbiosis II, LLC Common Stock 2025-12-12 4 S 0 7603 6.79 D 419460 I By Symbiosis II, LLC Common Stock 2025-12-15 4 S 0 10580 6.49 D 408880 I By Symbiosis II, LLC Common Stock 2025-12-16 4 S 0 7030 6.31 D 401850 I By Symbiosis II, LLC Common Stock 2025-12-17 4 S 0 2884 6.61 D 398966 I By Symbiosis II, LLC Common Stock 2025-12-18 4 S 0 5816 6.33 D 393150 I By Symbiosis II, LLC /s/Chidozie Ugwumba 2025-12-18