X0609 4 2026-09-16 0001822791 Clene Inc. CLNN 0001835537 Mosca Alison false 6550 SOUTH MILLROCK DRIVE SUITE G50 SALT LAKE CITY UT 84121 1 1 0 common stock 2026-09-16 4 A 0 198171 3.28 A 478671 I By LLC common stock 1973 D common stock 150333 I By LP common stock 72997 I By trust Kensington Clene 2021, LLC purchased 198,171 shares of common stock of Clene Inc. for a purchase price of $3.28 per share in a registered direct offering directly from the Issuer. The issuance of such securities was approved by the Issuer's board of directors in accordance with Rule 16 (b)-3 of the Securities Exchange Act of 1934, as amended. The securities are owned by Kensington Clene 2021, LLC. Ms. Mosca is the sole manager of and owns a minority interest in Kensington Clene 2021, LLC. The securities owned by Kensington Clene 2021, LLC may be deemed to be beneficially owned by Ms. Mosca. Ms. Mosca disclaims all securities owned by Kensington Clene 2021, LLC for which she does not have a pecuniary or profits interest. The securities are owned by Kensington Investments, L.P. Ms. Mosca is the chief executive officer of Kensington Investments, L.P. The securities owned by Kensington Investments, L.P. may be deemed to be beneficially owned by Ms. Mosca. Ms. Mosca disclaims all securities owned by Kensington Investments, L.P., for which she does not have a pecuniary or profits interest. The securities are owned by the Robert C. Gay 1998 Family Trust. Ms. Mosca is the trustee of the Robert C. Gay 1998 Family Trust. The securities owned by the Robert C. Gay 1998 Family Trust may be deemed to be beneficially owned by Ms. Mosca. Ms. Mosca has no pecuniary interest or profits interest in the securities held by the Robert C. Gay 1998 Family Trust. /s/ Jerome T. Miraglia POA 2026-09-18