X0202 SCHEDULE 13G 0001535978 XXXXXXXX LIVE Common Shares, no par value 06/30/2026 0001833141 Cybin Inc. 23256X407 100 King Street West Suite 5600 Toronto, Ontario A6 M5X 1C9 Rule 13d-1(b) Adage Capital Management, L.P. DE 0.00 3289250.00 0.00 3289250.00 3289250.00 N 5.29 IA PN Includes 229,250 Common Shares (as defined in Item 2(a)) issuable upon exercise of warrants. Robert Atchinson X1 0.00 3289250.00 0.00 3289250.00 3289250.00 N 5.29 HC IN Includes 229,250 Common Shares issuable upon exercise of warrants. Phillip Gross X1 0.00 3289250.00 0.00 3289250.00 3289250.00 N 5.29 HC IN Includes 229,250 Common Shares issuable upon exercise of warrants. Cybin Inc. 100 King Street West, Suite 5600, Toronto, Ontario, Canada M5X 1C9 This statement is filed by: (i) Adage Capital Management, L.P., a Delaware limited partnership ("ACM"), as the investment manager of Adage Capital Partners, L.P., a Delaware limited partnership ("ACP"), with respect to the common, no par value ("Common Shares") of Cybin Inc., a corporation incorporated under the laws of the Province of Ontario, Cananda (the "Company"), and Common Shares issuable upon exercise of warrants directly held by ACP; (ii) Robert Atchinson ("Mr. Atchinson"), as (1) managing member of Adage Capital Advisors, L.L.C., a limited liability company organized under the laws of the State of Delaware ("ACA"), managing member of Adage Capital Partners GP, L.L.C., a limited liability company organized under the laws of the State of Delaware ("ACPGP"), general partner of ACP and (2) managing member of Adage Capital Partners, L.L.C., a Delaware limited liability company ("ACPLLC"), general partner of ACM, with respect to the Common Shares and Common Shares issuable upon exercise of warrants directly held by ACP; and (iii) Phillip Gross ("Mr. Gross"), as (1) managing member of ACA, managing member of ACPGP and (2) managing member of ACPLLC, general partner of ACM, with respect to the Common Shares and Common Shares issuable upon exercise of warrants directly held by ACP. The foregoing persons are hereinafter sometimes collectively referred to as the "Reporting Persons." Any disclosures herein with respect to persons other than the Reporting Persons are made on information and belief after making inquiry to the appropriate party. The filing of this statement should not be construed in and of itself as an admission by any Reporting Person as to beneficial ownership of the securities reported herein. The address of the business office of each of the Reporting Persons is 200 Clarendon Street, 52nd Floor, Boston, Massachusetts 02116. ACM is a limited partnership organized under the laws of the State of Delaware. Messrs. Gross and Atchinson are citizens of the United States. N IA HC The information required by Item 4(a) is set forth in Row 9 of the cover page for each of the Reporting Persons and is incorporated herein by reference. The percentage set forth in this Schedule 13G is calculated based upon an aggregate of 61,984,078 Common Shares outstanding as of June 29, 2026, as reported in Exhibit 99.3 attached to the Company's Annual Report on Form 40-F for the fiscal year ended March 31, 2026, filed with the Securities and Exchange Commission on June 29, 2026, and assumes the exercise of warrants held by ACP. 5.29% The information required by Item 4(c)(i) is set forth in Row 5 of the cover page for each of the Reporting Persons and is incorporated herein by reference. The information required by Item 4(c)(ii) is set forth in Row 6 of the cover page for each of the Reporting Persons and is incorporated herein by reference. The information required by Item 4(c)(iii) is set forth in Row 7 of the cover page for each of the Reporting Persons and is incorporated herein by reference. The information required by Item 4(c)(iv) is set forth in Row 8 of the cover page for each of the Reporting Persons and is incorporated herein by reference. Y N See Item 2(a). Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11. Exhibit 99.1: Joint Filing Agreement Adage Capital Management, L.P. /s/ Robert Atchinson 08/12/2026 Robert Atchinson /s/ Robert Atchinson 08/12/2026 Phillip Gross /s/ Phillip Gross 08/12/2026