X0306 4 2021-11-19 0 0001832038 Adagio Therapeutics, Inc. ADGI 0001234124 MARRAM ELLEN R C/O ADAGIO THERAPEUTICS, INC. 1601 TRAPELO ROAD, SUITE 178 WALTHAM MA 02451 1 0 0 0 Stock Option (Right to Buy) 20.07 2021-11-19 4 A 0 62605 0.00 A 2031-11-18 Common Stock 62605 62605 D One third (1/3) of the option shall vest on November 19, 2022, and thereafter, the remainder of the option shall vest in 24 equal monthly installments on the 19th day of each month, subject to the Reporting Person's continuous service on each vesting date. /s/ Dorothy Vinsky, Attorney-in-Fact 2021-11-23