X0306 4 2021-08-05 0 0001832038 Adagio Therapeutics, Inc. ADGI 0001117003 MCGUIRE TERRANCE C/O ADAGIO THERAPEUTICS, INC. 303 WYMAN STREET, SUITE 300 WALTHAM MA 02451 1 0 0 0 Stock Option (Right to Buy) 17.00 2021-08-05 4 A 0 35593 0.00 A 2031-08-04 Common Stock 35593 35593 D One third (1/3) of the option shall vest on August 5, 2022, and thereafter, the remainder of the option shall vest in 24 equal monthly installments on the 5th day of each month, subject to the Reporting Person's continuous service on each vesting date. /s/ Dorothy Vinsky, Attorney-in-Fact 2021-08-09