CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Cash flows from operating activities:
Net loss	$ (151,656)	$ (83,373)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense	8,344	3,929
Non-cash payments	0	66
Net amortization of premiums and accretion of discounts on marketable securities	194	0
Amortization of operating lease right-of-use assets	211	0
Depreciation expense	9	0
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	18,825	(1,146)
Other non-current assets	2,998	0
Accounts payable	8,449	2,159
Accrued expenses	(3,653)	21,054
Other current liabilities	58	0
Operating lease liabilities	(214)	0
Other non-current liabilities	(6)	0
Net cash used in operating activities	(116,441)	(57,311)
Cash flows from investing activities:
Maturities of marketable securities	49,000	0
Purchases of property and equipment	(17)	0
Net cash provided by investing activities	48,983	0
Cash flows from financing activities:
Proceeds from issuance of convertible preferred stock, net of issuance costs paid	0	335,264
Payments of initial public offering costs	0	(432)
Proceeds from exercises of stock options	123	0
Payments for repurchases of unvested restricted common stock	(4)	0
Net cash provided by financing activities	119	334,832
Net (decrease) increase in cash and cash equivalents	(67,339)	277,521
Cash and cash equivalents at beginning of period	542,224	114,988
Cash and cash equivalents at end of period	474,885	392,509
Supplemental disclosure of non-cash investing and financing activities:
Operating lease right-of-use asset recognized upon adoption of ASC 842	1,728	0
Operating lease right-of-use asset recognized under ASC 842	1,344
Deferred offering and issuance costs included in accrued expenses	$ 0	$ 1,602